Involvement of 5-hydroxytryptamine-containing neurons in antinociception produced by injection of morphine into nucleus raphe magnus or onto spinal cord
MR Vasko, IH Pang, M Vogt - Brain research, 1984 - Elsevier
We studied whether antinociception produced by injection of morphine into the nucleus
raphe magnus (NRM) or superfusion onto the spinal cord involved serotonergic neurons that …
raphe magnus (NRM) or superfusion onto the spinal cord involved serotonergic neurons that …
Effects of intrathecally administered methysergide and yohimbine on microstimulation-produced antinociception in the rat
NM Barbaro, DL Hammond, HL Fields - Brain research, 1985 - Elsevier
This study examined whether intrathecal (it) administration of the serotonergic antagonist
methysergide, of theα 2 noradrenergic antagonist yohimbine, or of both drugs antagonized …
methysergide, of theα 2 noradrenergic antagonist yohimbine, or of both drugs antagonized …
Muscarinic and α1-adrenergic mechanisms contribute to the spinal mediation of stimulation-induced antinociception from the pedunculopontine tegmental nucleus in …
QM Dias, SF Crespilho, JWS Silveira… - … Biochemistry and Behavior, 2009 - Elsevier
The effects of intraperitoneal (ip) or intrathecal (it) injection of antagonists of acetylcholine,
noradrenaline, serotonin, dopamine, opioids and GABA on stimulation-produced …
noradrenaline, serotonin, dopamine, opioids and GABA on stimulation-produced …
Involvement of 5-hydroxytryptamine1A receptors in the descending anti-nociceptive pathway from periaqueductal gray to the spinal dorsal horn in intact rats, rats with …
ZY Liu, DB Zhuang, T Lunderberg, LC Yu - Neuroscience, 2002 - Elsevier
Studies have shown that 5-hydroxytryptamine (5-HT) plays an important role in the
descending pathway of pain modulation from brainstem to the spinal cord. Using selective 5 …
descending pathway of pain modulation from brainstem to the spinal cord. Using selective 5 …
5-Hydroxytryptamine 1A receptors in the dorsomedial hypothalamus connected to dorsal raphe nucleus inputs modulate defensive behaviours and mediate innate …
AF Biagioni, RC de Oliveira, R de Oliveira… - European …, 2016 - Elsevier
The dorsal raphe nucleus (DRN) is an important brainstem source of 5-hydroxytryptamine (5-
HT), and 5-HT plays a key role in the regulation of panic attacks. The aim of the present …
HT), and 5-HT plays a key role in the regulation of panic attacks. The aim of the present …
Roles of the rostroventromedial medulla and the spinal 5-HT1A receptor in descending antinociception induced by motor cortex stimulation in the neuropathic rat
H Viisanen, A Pertovaara - Neuroscience letters, 2010 - Elsevier
Electric stimulation of the primary motor cortex (M1) has been effective in suppressing pain-
related responses in neuropathic as well as healthy control animals. We studied whether the …
related responses in neuropathic as well as healthy control animals. We studied whether the …
Antinociceptive effect of ketanserin in mice: involvement of supraspinal 5-HT2 receptors in nociceptive transmission
AA Alhaider - Brain research, 1991 - Elsevier
The involvement of 5-HT 2 receptors in pain transmission was investigated in mice.
Subcutaneous administration of the selective 5-HT 2 receptor antagonist ketanserin …
Subcutaneous administration of the selective 5-HT 2 receptor antagonist ketanserin …
An ascending serotonergic pain modulation pathway from the dorsal raphe nucleus to the parafascicularis nucleus of the thalamus
E Andersen, N Dafny - Brain Research, 1983 - Elsevier
Three types of spontaneously active neurons were found in the parafascicularis (PF)
nucleus of the thalamus of the rat: slow firing units (0.5–10 spikes/s), bursting units (2–5 …
nucleus of the thalamus of the rat: slow firing units (0.5–10 spikes/s), bursting units (2–5 …
Intrathecal nefopam-induced antinociception through activation of descending serotonergic projections involving spinal 5-HT7 but not 5-HT3 receptors
HG Lee, WM Kim, JM Kim, HB Bae, JI Choi - Neuroscience Letters, 2015 - Elsevier
We examined the involvement of spinal 5-HT (5-hydroxytryptamine) receptor 3 (5-HT3R)
and 7 (5-HT7R) as well as the overall role of descending serotonergic projections in the …
and 7 (5-HT7R) as well as the overall role of descending serotonergic projections in the …
Spinal serotonin 5-HT7 and adenosine A1 receptors, as well as peripheral adenosine A1 receptors, are involved in antinociception by systemically administered …
J Liu, AR Reid, J Sawynok - European Journal of Pharmacology, 2013 - Elsevier
The present study explored a link between spinal 5-HT7 and adenosine A1 receptors in
antinociception by systemic amitriptyline in normal and adenosine A1 receptor knock-out …
antinociception by systemic amitriptyline in normal and adenosine A1 receptor knock-out …