Mesenchymal stromal cell-derived exosomes ameliorate peripheral neuropathy in a mouse model of diabetes
B Fan, C Li, A Szalad, L Wang, W Pan, R Zhang… - Diabetologia, 2020 - Springer
Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …
Exosomes derived from Schwann cells ameliorate peripheral neuropathy in type 2 diabetic mice
L Wang, M Chopp, A Szalad, XR Lu, Y Zhang… - Diabetes, 2020 - Am Diabetes Assoc
Schwann cell–derived exosomes communicate with dorsal root ganglia (DRG) neurons. The
current study investigated the therapeutic effect of exosomes derived from healthy Schwann …
current study investigated the therapeutic effect of exosomes derived from healthy Schwann …
Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified …
B Fan, M Chopp, ZG Zhang, XS Liu - Experimental neurology, 2021 - Elsevier
Diabetic peripheral neuropathy (DPN) is one of the most prevalent chronic complications of
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …
diabetes mellitus with no effective treatment. We recently demonstrated that mesenchymal …
Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction
Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …
Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through the NLRP3 signaling pathway
Y Wang, J Liu, H Wang, S Lv, Q Liu, S Li, X Yang… - Stem …, 2023 - academic.oup.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease worldwide.
Exosomes (Exo) derived from human umbilical cord mesenchymal stem cells (HUC-MSCs) …
Exosomes (Exo) derived from human umbilical cord mesenchymal stem cells (HUC-MSCs) …
[HTML][HTML] Transplantation of engineered exosomes derived from bone marrow mesenchymal stromal cells ameliorate diabetic peripheral neuropathy under electrical …
Diabetic peripheral neuropathy (DPN) is a long-term complication associated with nerve
dysfunction and uncontrolled hyperglycemia. In spite of new drug discoveries, development …
dysfunction and uncontrolled hyperglycemia. In spite of new drug discoveries, development …
Bone marrow-derived mesenchymal stem cells improve diabetes-induced cognitive impairment by exosome transfer into damaged neurons and astrocytes
M Nakano, K Nagaishi, N Konari, Y Saito, T Chikenji… - Scientific reports, 2016 - nature.com
The incidence of dementia is higher in diabetic patients, but no effective treatment has been
developed. This study showed that rat bone marrow mesenchymal stem cells (BM-MSCs) …
developed. This study showed that rat bone marrow mesenchymal stem cells (BM-MSCs) …
Human adipose mesenchymal stem cells modulate inflammation and angiogenesis through exosomes
JS Heo, S Kim - Scientific Reports, 2022 - nature.com
Stem cell-derived exosomes are efficient and safe therapeutic tools for transferring
endogenous biological cargo or functional biomolecules for regenerative medicine. The …
endogenous biological cargo or functional biomolecules for regenerative medicine. The …
Exosomes derived from human umbilical cord mesenchymal stem cells accelerate diabetic wound healing via promoting M2 macrophage polarization, angiogenesis …
L Teng, M Maqsood, M Zhu, Y Zhou, M Kang… - International journal of …, 2022 - mdpi.com
Some scholars have suggested that the clinical application of exosomes derived from
human umbilical cord mesenchymal stem cells (hucMSCs-exo) might represent a novel …
human umbilical cord mesenchymal stem cells (hucMSCs-exo) might represent a novel …
Mesenchymal stem cell-derived exosomes ameliorated diabetic nephropathy by autophagy induction through the mTOR signaling pathway
Background: Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and a
common cause of end-stage renal disease. Autophagy has a defensive role against kidney …
common cause of end-stage renal disease. Autophagy has a defensive role against kidney …