Background The presence of antibodies against the M-type phospholipase A2 receptor
(PLA2R-AB) is considered to be a promising serological diagnostic biomarker of idiopathic …

Materials and Methods In this mini review, the author searched English-language MEDLINE
for the terms “membranous nephropathy”,“rituximab”, and “phospholipase A2 receptor” up to …

Background: Rituximab has become one of the first-line therapies for the treatment of
moderate and high-risk primary membranous nephropathy (pMN). We retrospectively …

Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful for affirming the diagnosis of
idiopathic membranous nephropathy (IMN). Time-resolved fluoroimmunoassay (TRFIA) is …

Primary membranous nephropathy is a leading cause of adult nephrotic syndrome. The field
took a major step forward with the identification of phospholipase A2 receptor (PLA2R) as a …

Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1)
have been demonstrated to be very specific for idiopathic membranous nephropathy (MN) …

Epitope spreading is an immunologic phenomenon whereby an antibody or cellular
response to a given antigen may extend from one location on the antigen (epitope) to …

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome among
adults, which is the leading glomerular disease that recurs after kidney transplantation …

Membranous Nephropathy (MN) is an autoimmune disease associated with antibodies
against podocyte proteins: M-type phospholipase A2 receptor (PLA2R1) or thrombospondin …

Objectives This study aimed to establish time-resolved fluorescence immunoassays to
quantitatively detect the autoantibodies targeting different epitopes of M-type phospholipase …