Safety assessment of Oryeong-san, a traditional herbal formula: study of subacute toxicity and influence of cytochrome P450s and UDP-glucuronosyltransferases

WY Jeon, SE Jin, MY Lee, CS Seo, HK Shin… - Regulatory Toxicology …, 2018 - Elsevier
Oryeong-san is a traditional herbal formula that is used for the treatment of common
genitourinary diseases in Korea and other Asian countries. However, little is known about its …

Pharmacokinetic characterization of carnosol from rosemary (Salvia Rosmarinus) in male C57BL/6 mice and inhibition profile in human cytochrome P450 enzymes

B Vemu, R Tocmo, MC Nauman, SA Flowers… - Toxicology and Applied …, 2021 - Elsevier
Abstract Rosemary (Salvia Rosmarinus) is a rich source of dietary diterpenes with carnosol
as one of the major polyphenols used to standardize rosemary extracts approved as a food …

[HTML][HTML] Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats

G Wu, Z Dong, J Dong, L Wei, R Shi… - … Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
Terminalia chebula Retz.(TCR) is a medicinal material commonly used in Mongolian
medicine. After consulting the literature at home and abroad, current research on TCR …

The effect of MGCD0103 on CYP450 isoforms activity of rats by cocktail method

J Cai, Q Zhang, K Lin, L Hu… - BioMed Research …, 2015 - Wiley Online Library
MGCD0103, an isotype‐selective histone deacetylase inhibitor (HDACi), has been clinically
evaluated for the treatment of hematologic malignancies and advanced solid tumors, alone …

Effects of Wuji pill compound with different compatibility on cytochrome P450 CYP3A1/3A2 in rat liver microsomes in vitro

X Weng, Y Li, Q Yang, Y Wang, X Liu… - Zhongguo Zhong yao …, 2010 - europepmc.org
Objective Wuji pill is a prescription of traditional Chinese medicine (TCM) and was
composed of Rhizoma Coptidis, Fructus Evodiae Rutaecarpae and Radix Paeoniae Alba …

Modulation of Microsomal Cytochrome P450 by Scutellariae Radix and Gentianae Scabrae Radix in Rat Liver

JJ Kang, YC Chen, WC Kuo, T Chen… - The American journal …, 1996 - World Scientific
The present study has determined the effects of Scutellariae Radix (Huangqin) and
Gentianae scabrae Radix (Longdan) on liver microsomal cytochrome P450 (P450) …

Effects of continuous ingestion of herbal teas on intestinal CYP3A in the rat

K Matsuda, Y Nishimura, N Kurata, M Iwase… - Journal of …, 2007 - jstage.jst.go.jp
Tenryocha, rooibos, and guava teas are widely consumed as herbal beverages, especially
as a therapy against pollen allergy. To investigate the possible herbal tea-drug interaction …

Species difference in the metabolism of mulberrin in vitro and its inhibitory effect on cytochrome P450 and UDP-glucuronosyltransferase enzymes

J Hu, T Hu, Z Guo, Y Song, L Shan… - Chemical and …, 2022 - jstage.jst.go.jp
This study aimed to evaluate the interspecies difference in metabolism of mulberrin and
examine the interaction between mulberrin and CYP enzymes or recombinant human …

In Vitro inhibitory potential of decursin and decursinol angelate on the catalytic activity of cytochrome P-450 1A1/2, 2D15, and 3A12 isoforms in canine hepatic …

AM Abd El-Aty, SS Shah, BM Kim, JH Choi… - Archives of pharmacal …, 2008 - Springer
Danggui is one of the most popular herbal medicines consumed by patients in different
clinical settings in Asian countries. In this study, the two major pyranocoumarin compounds …

Effect of oligosaccharide esters and polygalaxanthone Ill from Polygala tenuifolia willd towards cytochrome P450

ZL Li, XZ Dong, DX Wang, RH Dong… - Zhongguo Zhong yao …, 2014 - europepmc.org
Five compounds (tenuifoliside C, tenuifoliside D, telephiose A, telephiose C and
polygalaxanthone III) from polygala tenuifolia wild were incubated together with CYP probe …