Complete surgical resection of malignant disease is the only reliable method to cure cancer.
Unfortunately, quantitative tumor resection is often limited by a surgeon's ability to locate all …

Because the most reliable therapy for cancer involves quantitative resection of all diseased
tissue, considerable effort has been devoted to improving a surgeon's ability to locate and …

Tumor-targeted near-infrared fluorescent dyes have the potential to improve cancer surgery
by enabling surgeons to locate and resect more malignant lesions where good visualization …

Conspectus Near-infrared (NIR) fluorescence light has been widely utilized in clinical
imaging by providing surgeons highly specific images of target tissue. The “NIR window” …

Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

Molecular imaging using near-infrared (NIR) fluorescence is useful for intraoperative
imaging and real-time margin identification. Directly conjugated IR dyes possess useful …

Small-molecular targeted probes for biological imaging can be effective for overcoming in
vivo delivery barriers often encountered by large affinity molecules such as monoclonal …

Fluorescence-guided surgery using tumour-targeted imaging agents has emerged over the
past decade as a promising and effective method of intraoperative cancer detection. An …

Surgical resection of solid tumors is currently the most efficient and preferred therapeutic
strategy for treating cancer. Despite significant medical, technical, and scientific advances …

Cancer surgery remains the primary treatment option for most solid tumors and can be
curative if all malignant cells are removed. Surgeons have historically relied on visual and …