Immunomodulation is a powerful therapeutic approach that harnesses the body's own
immune system and reprograms it to treat diseases, such as cancer. Innate immunity is key …

The discovery of immune checkpoint blockade has revolutionized the field of immuno‐
oncology and established the foundation for developing various new therapies that can …

Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity,
and infection. While exciting, most of the existing therapies are limited by their specificity─ …

Cancer immunotherapy has achieved promising clinical results. However, many limitations
associated with current cancer immunotherapy still exist, including low response rates and …

Immunotherapy is a promising treatment modality for cancer as it can promote specific and
durable anti-cancer responses. However, limitations to current approaches remain …

Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …

Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …

Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

Biomaterial carriers offer modular features to control the delivery and presentation of
vaccines and immunotherapies. This tunability is a distinct capability of biomaterials …