Combined use of liquid chromatography–hybrid quadrupole time-of-flight mass spectrometry (LC–QTOF-MS) and high performance liquid chromatography with …

S Broecker, F Pragst, A Bakdash, S Herre… - Forensic science …, 2011 - Elsevier
Time of flight mass spectrometry provides new possibilities of substance identification by
determination of the molecular formula from accurate molecular mass and isotope pattern …

[HTML][HTML] Illicit drugs street samples and their cutting agents. The result of the GC-MS based profiling define the guidelines for sensors development

A Żubrycka, A Kwaśnica, M Haczkiewicz, K Sipa… - Talanta, 2022 - Elsevier
In this work, we have focused on the profiling of 5647 street samples covering marijuana,
common and new recreational illicit drugs. All samples were analyzed using gas …

Rapid sample pre-treatment prior to GC–MS and GC–MS/MS urinary toxicological screening

F Versace, F Sporkert, P Mangin, C Staub - Talanta, 2012 - Elsevier
Drug screening is an important issue in clinical and forensic toxicology. Gas
chromatography coupled to mass spectrometry (GC–MS) remains the gold standard …

[HTML][HTML] Development and validation of a single step GC/MS method for the determination of 41 drugs and drugs of abuse in postmortem blood

A Orfanidis, A Krokos, O Mastrogianni, H Gika… - Forensic Sciences, 2022 - mdpi.com
A toxicology laboratory often receives a high number of samples from cases (autopsies or
clinical) that may require the quick delivery of trustworthy, accurate results. Thus, there is a …

Urine toxicology screening by liquid chromatography time-of-flight mass spectrometry in a quaternary hospital setting

JD Pope, MJ Black, OH Drummer, HG Schneider - Clinical Biochemistry, 2021 - Elsevier
Objective Validation of a non-targeted method for urine drug screening (UDS) by liquid
chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF), and comparison to …

Multicomponent LC–MS/MS screening method for detection of new psychoactive drugs, legal highs, in urine—experience from the Swedish population

Y Al-Saffar, NN Stephanson, O Beck - Journal of Chromatography B, 2013 - Elsevier
The advent of new not yet legally regulated psychoactive substances sold over the Internet
has created a challenge for clinical toxicology and drug testing laboratories. The routine use …

Patterns of drug abuse among drug users with regular and irregular attendance for treatment as detected by comprehensive UHPLC‐HR‐TOF‐MS

M Sundström, A Pelander, K Simojoki… - Drug testing and …, 2016 - Wiley Online Library
The most severe consequences of drug abuse include infectious diseases, overdoses, and
drug‐related deaths. As the range of toxicologically relevant compounds is continually …

Characterization and identification of eight designer benzodiazepine metabolites by incubation with human liver microsomes and analysis by a triple quadrupole mass …

S El Balkhi, M Chaslot, N Picard, S Dulaurent… - International journal of …, 2017 - Springer
Designer benzodiazepines (DBZDs) have become of particular importance in the past few
years. The metabolite monitoring of DBZD in biological fluids could be of great interest in …

Quantification of five compounds with heterogeneous physicochemical properties (morphine, 6-monoacetylmorphine, cyamemazine, meprobamate and caffeine) in 11 …

F Bevalot, C Bottinelli, N Cartiser… - Journal of analytical …, 2014 - academic.oup.com
An automated solid-phase extraction (SPE) protocol followed by gas chromatography
coupled with tandem mass spectrometry was developed for quantification of caffeine …

LC-MS-MS vs ELISA: validation of a comprehensive urine toxicology screen by LC-MS-MS and a comparison of 100 forensic specimens

KW Kahl, JZ Seither, LJ Reidy - Journal of analytical toxicology, 2019 - academic.oup.com
Toxicology laboratories commonly employ immunoassay methodologies to perform an initial
drug screen on urine specimens to direct confirmatory testing. Due to limitations of …