The cerebrospinal fluid (CSF) features a unique immune cell composition and is in constant
contact with the brain borders, thus permitting insights into the brain to diagnose and monitor …

Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF
aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains …

T cells provide critical immune surveillance to the central nervous system (CNS), and the
cerebrospinal fluid (CSF) is thought to be a main route for their entry. Further …

Individual reports suggest that the central nervous system (CNS) contains multiple immune
cell types with diverse roles in tissue homeostasis, immune defense, and neurological …

Brain–immune cross-talk and neuroinflammation critically shape brain physiology in health
and disease. A detailed understanding of the brain immune landscape is essential for …

Peripheral central nervous system (CNS)–infiltrating lymphocytes are a hallmark of
relapsing-remitting multiple sclerosis. Tissue-resident memory T cells (TRM) not only …

The innate immune compartment of the human central nervous system (CNS) is highly
diverse and includes several immune-cell populations such as macrophages that are …

Despite the overwhelming evidence that multiple sclerosis is an autoimmune disease,
relatively little is known about the precise nature of the immune dysregulation underlying the …

The CNS has traditionally been considered an immune privileged site, but is now
understood to have a system of immune surveillance, predominantly involving CD4+ T-cells …

Central nervous system B cells have several potential roles in multiple sclerosis (MS):
secretors of proinflammatory cytokines and chemokines, presenters of autoantigens to T …