Sickle cell disease in children: an update of the evidence in low-and middle-income settings

I Odame - Archives of Disease in Childhood, 2023 - adc.bmj.com
Sickle cell disease (SCD), one of the most common monogenetic diseases in the world, is
associated with multisystemic complications that begin in childhood. Most of the babies …

Sickle Cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub‐Saharan Africa and Beyond

WI Egesa, G Nakalema, WM Waibi… - … Journal of Pediatrics, 2022 - Wiley Online Library
Sickle cell disease (SCD) is an umbrella term for a group of life‐long debilitating autosomal
recessive disorders that are caused by a single‐point mutation (Glu→ Val) that results in …

Sickle cell disease: a neglected chronic disease of increasing global health importance

S Chakravorty, TN Williams - Archives of disease in childhood, 2015 - adc.bmj.com
Sickle cell disease (SCD) is a single gene disorder causing a debilitating systemic
syndrome characterised by chronic anaemia, acute painful episodes, organ infarction and …

Overview of current progress and challenges in diagnosis, and management of pediatric sickle cell disease in Democratic Republic of the Congo

ET Kasai, JP Alworong'a Opara… - …, 2022 - Taylor & Francis
Objectives Sickle cell disease (SCD) encompasses health complications, primarily affecting
the hematologic system and leading to high death rates in childhood. As a rule, the World …

Sickle cell disease: Translating clinical care to low-resource countries through international research collaborations

LR Smart, AG Hernandez, RE Ware - Seminars in hematology, 2018 - Elsevier
The vast majority of the world's population of children and adults with sickle cell disease
(SCD) are born in low-resource settings, particularly in sub-Saharan Africa, the Caribbean …

Improving outcomes in children with sickle cell disease: treatment considerations and strategies

A Amid, I Odame - Pediatric Drugs, 2014 - Springer
Over the past decades there has been a significant improvement in the care of patients with
sickle cell disease (SCD) in high-income countries. However, more needs to be learned …

[HTML][HTML] Sickle cell disease among children in Africa: an integrative literature review and global recommendations

LL Mulumba, L Wilson - International Journal of Africa Nursing Sciences, 2015 - Elsevier
Sickle cell disease (SCD) is a genetic blood disorder affecting red blood cells, with high
morbidity and mortality rates. The United Nations has recognized SCD as a global public …

Characterisation of medical conditions of children with sickle cell disease in the USA: findings from the 2007–2018 National Health Interview Survey (NHIS)

J Gyamfi, S Tampubolon, JT Lee, F Islam, T Ojo… - BMJ open, 2023 - bmjopen.bmj.com
Objectives We used the National Health Interview Survey (NHIS) data set to examine the
prevalence of comorbid medical conditions; explore barriers to accessing healthcare and …

Sickle cell disease: an update on management

J Brewin, J Howard - Paediatrics and Child Health, 2017 - Elsevier
Sickle cell disease (SCD) is a common inherited disease affecting 12–15,000 individuals in
the UK with approximately 250 new births per annum. Life expectancy has improved with the …

Sickle cell disease: progress made & challenges ahead

I Odame, D Jain - Indian Journal of Medical Research, 2020 - journals.lww.com
About seven per cent of the world's population is a carrier of globin-gene mutations1, of
which the sickle gene is one of the most common and the most pathogenic [sickle cell …