Background and objective: Mounting studies have illustrated an important role of autophagy
in various diseases, but few studies have reported its contribution to rheumatoid arthritis …

Objective This study aims to explore the relationship between PI3K/AKT/mTOR signaling
pathway and autophagy of articular chondrocytes in rats with osteoarthritis (OA). Methods …

Tumor Necrosis Factor‐alpha (TNF‐α) was reported to increase autophagy in rheumatoid
arthritis human fibroblast‐like synovial cell (RA‐HFLS). We investigated different levels of …

Objective To investigate the role of autophagy in the regulation of cell death in rheumatoid
arthritis synovial fibroblasts (RASFs). Methods RASFs and osteoarthritis synovial fibroblasts …

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that eventually leads
to joint deformities and loss of joint function. Previous studies have demonstrated a close …

Autophagy is considered as an important intracellular mechanism that degrades cytoplasmic
components to furnish additional energy. It has cytoprotective effects through the …

Rheumatoid arthritis (RA) is a common chronic autoimmune disease, which seriously harms
human health. The hyperplastic growth of fibroblast-like synoviocytes (FLSs) plays a key role …

Background Recent studies have shown that autophagy was associated with the
development of osteoarthritis (OA), the purpose of this research was to determine the exact …

Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage
degeneration and abnormal bone remodeling in the subchondral bone. Autophagy …

Introduction Programmed cell death of intervertebral disc (IVD) cells plays an important role
in IVD degeneration, but the role of autophagy, a closely related cell death event, in IVD …