[HTML][HTML] Challenges and limitations of strategies to promote therapeutic potential of human mesenchymal stem cells for cell-based cardiac repair

TVA Bui, JW Hwang, JH Lee, HJ Park… - Korean Circulation …, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) represent a population of adult stem cells residing in many
tissues, mainly bone marrow, adipose tissue, and umbilical cord. Due to the safety and …

Mesenchymal stem cell therapy for cardiac repair

R Thakker, P Yang - Current treatment options in cardiovascular medicine, 2014 - Springer
Opinion statement Owing to the prevalence of heart disease and the lack of effective long-
term solutions for managing cardiac injury, research has turned to cell therapy as a potential …

Modification of mesenchymal stem cells for cardiac regeneration

H Song, BW Song, MJ Cha, IG Choi… - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Mesenchymal stem cells (MSCs) have the greatest potential for use
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …

Functions of mesenchymal stem cells in cardiac repair

S Öztürk, AE Elçin, YM Elçin - … Medicine, Volume 11: Stem Cell Therapy …, 2020 - Springer
Myocardial infarction (MI) and heart failure (HF) are significant contributors of mortality
worldwide. Mesenchymal stem cells (MSCs) hold a great potential for cardiac regenerative …

The roles of mesenchymal stem cells (MSCs) therapy in ischemic heart diseases

XJ Wang, QP Li - Biochemical and biophysical research communications, 2007 - Elsevier
Growing cell-based myocardial therapies which could lead to successful myocardial repair
attracts medical interest. Even more intriguing is the observation that MSCs appears to be a …

[HTML][HTML] Mesenchymal stem cells for cardiac regenerative therapy: optimization of cell differentiation strategy

H Shen, Y Wang, Z Zhang, J Yang, S Hu… - Stem cells …, 2015 - hindawi.com
With the high mortality rate, coronary heart disease (CHD) has currently become a major life-
threatening disease. The main pathological change of myocardial infarction (MI) is the …

[HTML][HTML] Mesenchymal stem cells for the treatment of heart disease

K Yamahara, N Nagaya - 2007 - Future Medicine
Despite recent progress in treatment, coronary heart disease and heart failure are the major
causes of morbidity and mortality in the Western world. Therefore, cell therapy is currently …

[HTML][HTML] How to improve the survival of transplanted mesenchymal stem cell in ischemic heart?

L Li, X Chen, WE Wang, C Zeng - Stem Cells International, 2016 - hindawi.com
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

Mesenchymal stem cell insights: prospects in cardiovascular therapy

SH Chou, SZ Lin, WW Kuo, P Pai, JY Lin… - Cell …, 2014 - journals.sagepub.com
Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …

Mesenchymal stem cells in cardiac repair: effects on myocytes, vasculature, and fibroblasts

SJ White, JJH Chong - Clinical therapeutics, 2020 - Elsevier
Purpose Cardiac pathologies remain a dominant cause of morbidity and mortality within the
community. The drive to develop therapies capable of repairing damaged heart tissue to …