No evidence for persistence of BCR-ABL–positive cells in patients in molecular remission after conventional allogeneic transplantation for chronic myeloid leukemia
M Deininger, T Lehmann, R Krahl… - Blood, The Journal …, 2000 - ashpublications.org
Blood ASH 96/2 treatment with BMT, and serial samples were analyzed for levels of
genomic and mRNA BCR-ABL using DNA-PCR with patientspecific primers and RT-PCR …
genomic and mRNA BCR-ABL using DNA-PCR with patientspecific primers and RT-PCR …
Apparent decrease and elimination of BCR/ABL mRNA-expressing residual cells in patients with chronic myelogenous leukemia after allogeneic bone marrow …
W Lange, R Herkert, J Finke, U Ragoczy, W Siegert… - Annals of …, 1991 - Springer
A modified two-step polymerase chain reaction (PCR) was used for the amplification of
BCR/ABL mRNA in 16 patients with Philadelphia chromosomepositive (Ph+) chronic …
BCR/ABL mRNA in 16 patients with Philadelphia chromosomepositive (Ph+) chronic …
Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous …
In chronic myelogenous leukemia (CML), amplification of a segment of bcr-abl messenger
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …
RNA (mRNA) by polymerase chain reaction (PCR) can be used to detect minimal residual …
bcr/abl mRNA detection following bone marrow transplantation for chronic myelogenous leukemia
P Ely, WJ Miller - Transplantation, 1991 - journals.lww.com
We have utilized the polymerase chain reaction (PCR) to sensitively detect persistence of
the chronic myelogenous leukemia (CML) malignant clone and to study bcr/abl mRNA …
the chronic myelogenous leukemia (CML) malignant clone and to study bcr/abl mRNA …
Serial measurement of BCR-ABL transcripts in the peripheral blood after allogeneic stem cell transplantation for chronic myeloid leukemia: an attempt to define …
We identified 243 patients with Philadelphia (Ph) chromosome–positive chronic myeloid
leukemia (CML) who had BCR-ABL transcripts monitored by quantitative reverse …
leukemia (CML) who had BCR-ABL transcripts monitored by quantitative reverse …
Presence or re-appearance of BCR-ABL-positive cells years after allogeneic bone marrow transplantation for chronic-phase chronic myelogenous leukemia in …
L Diekmann, DW Beelen, K Quabeck, R Becher… - Acta …, 1994 - karger.com
AUogeneic bone marrow transplantation (BMT) is considered to be the only curative therapy
for chronic myelogenous leukemia (CML). The cytogenetic marker of CML, the Philadelphia …
for chronic myelogenous leukemia (CML). The cytogenetic marker of CML, the Philadelphia …
Persistence of bcr-abl gene expression following bone marrow transplantation for chronic myelogenous leukemia in chronic phase
DS SNYDER, JJ ROSSI, JLIN WANG… - …, 1991 - journals.lww.com
The bcr-abl RNA transcript is the molecular counterpart of the Philadelphia chromosome
and is detectable by an extremely sensitive polymerase chain reaction assay in most …
and is detectable by an extremely sensitive polymerase chain reaction assay in most …
Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in …
We studied 346 patients after bone marrow transplantation (BMT) for chronic myeloid
leukemia (CML) for the presence of the bcr-abl transcript detected by the polymerase chain …
leukemia (CML) for the presence of the bcr-abl transcript detected by the polymerase chain …
Clinical Significance of bcr-abl Gene Rearrangement Detected by the Polymerase Chain Reaction After Allogeneic Bone Marrow Transplantation in Chronic …
G Pichert, J Ritz - Leukemia & Lymphoma, 1993 - Taylor & Francis
Although serial detection of bcr-abl positive cells by PCR appears able to identify distinct
patient groups with different risks of relapse following BMT, there remain many unanswered …
patient groups with different risks of relapse following BMT, there remain many unanswered …
Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …
K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …