Sepsis remains the leading cause of death in most intensive care units. Advances in
understanding the immune response to sepsis provide the opportunity to develop more …

Sepsis with subsequent multiple organ dysfunction is a pronounced systemic inflammatory
response to concealed or known infection and is a leading cause of death in intensive care …

Despite advances in critical care medicine, mortality from sepsis in ICU patients remains
high. In response to several infectious and non-infectious stimuli, monocytes/macrophages …

The often fatal sepsis syndrome is characterized by the systemic release of inflammatory
mediators, which is regulated and counterbalanced by the coordinated expression of anti …

Neuronal stimulation is an emerging field in modern medicine to control organ function and
re-establish physiological homeostasis during illness. Transdermal nerve stimulation with …

Purpose Sepsis remains an unresolved clinical problem with high in-hospital mortality.
Despite intensive research over decades, no treatments for sepsis have become available …

Background Anti-inflammatory cytokine effects of vagus nerve stimulation in sepsis
syndromes are well established. Effects on immune cells are less clear. Therefore, we …

Sepsis-associated encephalopathy (SAE), the most popular cause of coma in the intensive
care unit (ICU), is the diffuse cerebral damage caused by the septic challenge. SAE is …

Despite the advances in the therapeutic approaches, health care protocols and policies,
sepsis continues to be an important problem in clinical medicine. High lethality of sepsis …

Sepsis is triggered by infection-induced immune alteration and may be theoretically
improved by pharmacological and extracorporeal immune modulating therapies …