Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …

In spite of over half a century of research, sepsis still constitutes a major problem in health
care delivery. Although advances in research have significantly increased our knowledge of …

Inflammation contributes to the pathogenesis of a wide variety of disorders including kidney
diseases. Recent advances have shown that neural pathways are able to regulate immunity …

The spectrum of sepsis and septic shock remains a highly prevalent disease state, carrying
a high risk of morbidity and mortality. The sympathetic nervous system (SNS) plays an …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Sepsis is a life-threatening condition and a global disease burden. Today, the
heterogeneous syndrome is defined as severe organ dysfunction caused by a dysregulated …

BACKGROUND: Sepsis and secondary multiple organ failure in critically ill patients are the
major cause of death, but the pathogenesis of sepsis is not clear, especially the dysfunction …

Severe burn-induced inflammation and subsequent hypermetabolic response can lead to
profound infection and sepsis, resulting in multiple organ failure and high mortality risk in …

The immune response of the host against invading pathogens is clinically manifested as
sepsis. Sepsis is a complicated process characterized by distinct phases that usually occur …

Sepsis-associated encephalopathy (SAE) is commonly complicated by septic conditions,
and is responsible for increased mortality and poor outcomes in septic patients …