Introduction Human T-lymphotropic virus type 1 (HTLV-1) is a lifelong persistent retrovirus
associated with numerous systemic and ocular diseases, presenting significant clinical …

Lupeol is a pentacyclic triterpene with known anti-inflammatory effects. However, its role in
the treatment of noninfectious uveitis has not been explored. This work investigated anti …

We investigated the suppressive effect of triptolide (TRD), a purified component from a
traditional Chinese herb, Tripterygium wilfordii Hook F.(TWHf), on uveitogenic peptide (K2) …

The purpose of the study was to investigate the anti-inflammatory efficiency of vorinostat, a
histone deacetylase inhibitor, in experimental autoimmune uveitis (EAU). EAU was induced …

Introduction Japan is the most endemic of the developed nations in terms of human T-
lymphotropic virus type 1 (HTLV-1) infection. Japan has been tackling HTLV-1 infection and …

Use of biologics has been widely advocated for inflammatory diseases recently. Anti-tumor
necrosis factor (TNF)-α antibody therapy is reportedly effective against ocular inflammation …

There is growing interest in evaluating the safety and therapeutic potential of existing
treatments such as tocilizumab (TCZ), an IL-6 receptor antagonist used to treat inflammatory …

Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus described as a
causative agent for human disease. In the field of ophthalmology, a close relationship …

Ocular hypertension (OHT) caused by inflammation or corticosteroid treatment is a common
complication of uveitis. Ripasudil hydrochloride hydrate (K-115) is reportedly efficacious for …

Background Uveitis is a potentially blinding inflammatory disease of the inner eye with a
high unmet need for new therapeutic interventions. Here, we wanted to investigate the …