We reported HTIN-1 uveitis (FLU) as the third distinct clinical entity associated with HTLV-1
infection, Uveitis has advantages for studying the pathogenetic mechanisms of inflammatory …

Purpose To study the effects of triptolide, a Chinese herb extract, on retinal ganglion cells
(RGCs) in a rat model of chronic glaucoma. Methods Eighty Wistar rats were randomly …

Background Glaucoma, the leading cause of irreversible blindness worldwide, is a type of
retinal disease characterized by the selective death of retinal ganglion cells (RGCs) …

TLRs are critical for host defense and innate immunity. Emerging evidence also supports a
role for TLRs in many chronic inflammatory diseases, including inflammatory eye disease …

Purpose The aim of this study is to investigate the anti-inflammatory effect of Radix Hedysari
Polysaccharide (HPS) on clinical indicators, the expression of Toll-like receptor-4 (TLR4) …

Purpose Inflammation triggers the activation of CD4+ T cells and the breakdown of blood–
retinal barrier, thus contributing to the pathology of experimental autoimmune uveitis (EAU) …

Aims: The aim of this study was to investigate the effects of pyrrolidine dithiocarbamate
(PDTC), a nuclear factor (NF)-κB inhibitor, on cytokine expression and suppression of …

Purpose: Antimicrobial peptides (AMPs) and toll-like receptors (TLRs) form part of the
“chemical barrier” of the ocular surface to microbes. Evidence suggests that pathogen …

AIM To investigate the efficacy of ripasudil, a Rho kinase inhibitor, in reducing intraocular
pressure (IOP) and medication scores of anti-glaucoma drugs in patients with ocular …

In recent years, glaucoma has been proposed as an autoimmune disease and an
understanding immune-regulation concept has been applied for novel glaucoma therapy …