Purpose: To investigate a clinical survey of uveitis in southern Kyushu of Japan, where
human T-lymphotropic virus type 1 (HTLV-1) and toxoplasmosis is highly endemic. Methods …

Glaucoma is a complex neurodegenerative disorder characterized by the progressive loss of
retinal ganglion cells (RGC) and optic nerve axons, leading to irreversible visual impairment …

AIM To identify the effect of Houttuynia cordata Thunb (HCT) on lipopolysaccharide (LPS)-
induced microglial activation and investigate its possible molecular mechanisms. METHODS …

The constant exposure of ocular surface to external environment and then to several
microbial agents is often related to the pathogenesis of various inflammatory eye disorders …

Chronic and recurrent uveitis account for approximately 10% of legal blindness in the
western world. Autoimmune uveitis is driven by activated CD4+ T cells that differentiate into …

To create a novel animal model of ocular hypertension via the intracameral injection of
Healaflow. Unilateral chronic ocular hypertension model of rats was created by the …

Purpose: To determine the immunologic functions of TRPA1 or TRPV1 in allergic
conjunctivitis (AC). Methods: Mice were sensitized with ovalbumin (OVA), after which TRPA1 …

The local interaction between retinal pigment epithelium (RPE) and immigrated effector T
cells is crucial for the pathogenesis of autoimmune uveitis. After being activated by the …

Abstract Background HTLV-1-associated uveitis (HAU) is an inflammatory reaction of the
choroid, retina, optic nerve and vitreous that can lead to vision impairment. The worldwide …

Purpose.: To investigate the role of Toll-like receptors (TLRs) 2, 3, 4, and 8 in the
pathogenesis of Behcet's disease (BD). Methods.: Sixteen patients with active ocular BD and …