Background Inflammation of RPE cells led to different kinds of eye diseases and affected the
normal function of the retina. Furthermore, higher levels of ROCK1 and ROCK2 induced …

PURPOSE: To verify the occurrence of keratoconjunctivitis sicca (KCS) and human T-cell
lymphotropic virus type 1 (HTLV-1) associated uveitis (HAU) and to evaluate the …

Purpose: To investigate the anti-inflammatory properties of ripasudil, a Rho kinase (ROCK)
inhibitor, using endotoxin-induced uveitis (EIU) in rats. Methods: Endotoxin-induced uveitis …

Objective Toll-like receptor 4-mediated acute anterior uveitis is a serious ocular
inflammatory disease, and new targeted drug therapy is the primary treatment. The objective …

Purpose. To evaluate the effect of a traditional Chinese medicine, Rheum Polysaccharide
(RP), on the in vitro production of tumor necrosis factor alpha (TNF‐α) and interleukin‐10 (IL …

Purpose.: Behçet's disease (BD) is a chronic systemic inflammatory disorder of unknown
etiology. Toll-like receptors (TLRs) are critical in the innate immune response to microbial …

Purpose: Increased interferon gamma (IFN-γ) expression in dry eye causes ocular surface
epithelial disease termed keratoconjunctivitis sicca (KCS). The purpose of this study was to …

Introduction: Among the intraocular pressure (IOP)-lowering drugs used in a clinical setting,
Rho kinase (ROCK) inhibitors lower IOP by a unique mechanism, namely the …

Dry eye disease (DED) is a multifactorial ocular disorder that interferes with daily living and
reduces quality of life. However, there is no most ideal therapeutic treatment to address all …

ABSTRACT Herpes simplex virus 1 (HSV-1) infects eye corneal tissues leading to herpetic
stromal keratitis (HSK), which is one of the leading causes of blindness. Here in our study …