Identification of a 90-kDa polypeptide which associates with adenovirus VA RNAI and is phosphorylated by the double-stranded RNA-dependent protein kinase

AP Rice, M Kostura, MB Mathews - Journal of Biological Chemistry, 1989 - Elsevier
Interferon treatment of mammalian cells induces a double-stranded (ds) RNA-dependent
protein kinase known as DAI. When activated, DAI phosphorylates the α-subunit of …

Control region for adenovirus VA RNA transcription.

R Guilfoyle, R Weinmann - Proceedings of the National …, 1981 - National Acad Sciences
Plasmids containing the VA RNA genes of adenovirus are faithfully transcribed by a crude
cytoplasmic extract containing DNA-dependent RNA polymerase III [Wu, G.-J.(1978) Proc …

Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2.

G Akusjärvi, MB Mathews… - Proceedings of the …, 1980 - National Acad Sciences
A DNA sequence, 552 base pairs in length, encoding the two" virus-associated"(VA) RNAs
of adenovirus type 2 is presented. Comparison of the oligonucleotide maps of VA RNAI and …

RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and in vivo

JL Manley, PA Sharp, ML Gefter - Journal of Molecular Biology, 1979 - Elsevier
Nuclei isolated from HeLa cells 16 hours post infection by adenovirus serotype 2 synthesize
high levels of viral specific RNA in vitro. This RNA shares many features in common with …

Biochemical studies on adenovirus multiplication: XV. Transcription of the adenovirus type 2 genome during productive infection

DC Thomas, M Green - Virology, 1969 - Elsevier
The viral genome is transcribed sequentially in adenovirus type 2-infected KB cells. About
one-fifth of the viral genome is transcribed prior to DNA synthesis by 6 hours after infection …

Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vectors.

RJ Kaufman - Proceedings of the National Academy of …, 1985 - National Acad Sciences
A transient expression system was used to study the role of the adenovirus late and simian
virus 40 (SV40) early mRNA leader sequences and adenovirus virus-associated (VA) RNAs …

Inhibition of HeLa cell protein synthesis during adenovirus infection: restriction of cellular messenger RNA sequences to the nucleus

GA Beltz, SJ Flint - Journal of molecular biology, 1979 - Elsevier
The mechanism by which adenovirus type 2 inhibits HeLa cell protein synthesis has been
investigated by a quantitative analysis of the synthesis and metabolism of cellular and viral …

Effect of adenovirus on metabolism of specific host mRNAs: transport control and specific translational discrimination

A Babich, LT Feldman, JR Nevins… - … and Cellular Biology, 1983 - Taylor & Francis
We have studied the adenovirus-induced inhibition of host cell protein synthesis and the
effect of infection on the overall metabolism of host cell mRNA during the late phase of …

Organization of the double-stranded rna-activated protein kinase dai and virus-associated va rnai in adenovirus-2-infected hela cells

LF Jiménez-García, SR Green… - Journal of cell …, 1993 - journals.biologists.com
We have examined the cellular distribution of the double-stranded RNA-activated protein
kinase DAI in adenovirus 2 (Ad2)-infected and uninfected HeLa cells. In uninfected cells DAI …

Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus

WK Hoeffler, RG Roeder - Cell, 1985 - cell.com
Nuclear extracts from adenovirus-infected HeLa cells harvested early in infection
demonstrated a markedly increased capacity for transcription by RNA polymerase III of …