[HTML][HTML] Identification of potential diagnoses based on immune infiltration and autophagy characteristics in major depressive disorder

Y Sun, J Li, L Wang, T Cong, X Zhai, L Li, H Wu… - Frontiers in …, 2022 - frontiersin.org
Background: Major depressive disorder (MDD) is a serious mental illness characterized by
mood changes and high suicide rates. However, no studies are available to support a blood …

Signatures of 4 autophagy-related genes as diagnostic markers of MDD and their correlation with immune infiltration

S He, Z Deng, Z Li, W Gao, D Zeng, Y Shi… - Journal of affective …, 2021 - Elsevier
Background Major depressive disorder (MDD) is a debilitating mental illness and one of the
primary causes of suicide. This study attempted to develop and validate a multigene joint …

[HTML][HTML] Identification of diagnostic markers for major depressive disorder by cross-validation of data from whole blood samples

H Wang, M Zhang, Q Xie, J Yu, Y Qi, Q Yue - PeerJ, 2019 - peerj.com
Background Major depressive disorder (MDD) is a severe disease characterized by multiple
pathological changes. However, there are no reliable diagnostic biomarkers for MDD. The …

[HTML][HTML] Identification of mitophagy-related biomarkers and immune infiltration in major depressive disorder

J Zhang, S Xie, R Xiao, D Yang, Z Zhan, Y Li - BMC genomics, 2023 - Springer
Background Major depressive disorder (MDD) is a life-threatening and debilitating mental
health condition. Mitophagy, a form of selective autophagy that eliminates dysfunctional …

[HTML][HTML] A novel 4 immune-related genes as diagnostic markers and correlated with immune infiltrates in major depressive disorder

L Ning, Z Yang, J Chen, Z Hu, W Jiang, L Guo, Y Xu… - BMC immunology, 2022 - Springer
Background Immune response is prevalently related with major depressive disorder (MDD)
pathophysiology. However, the study on the relationship between immune-related genes …

[HTML][HTML] Identification of key genes and the pathophysiology associated with major depressive disorder patients based on integrated bioinformatics analysis

G Zhang, S Xu, Z Zhang, Y Zhang, Y Wu, J An… - Frontiers in …, 2020 - frontiersin.org
Background: At present, laboratory blood tests to support major depressive disorder (MDD)
diagnosis are not available. This study aimed to screen potential mRNAs for peripheral …

[HTML][HTML] Identification of novel endoplasmic reticulum-related genes and their association with immune cell infiltration in major depressive disorder

L Chang, T Wang, Y Qu, X Fan, X Zhou, Y Wei… - Journal of Affective …, 2024 - Elsevier
Background Several lines of evidence point to an interaction between genetic predisposition
and environmental factors in the onset of major depressive disorder (MDD). This study is …

Identification of 7 mitochondria-related genes as diagnostic biomarkers of MDD and their correlation with immune infiltration: New insights from bioinformatics analysis

X Liu, Y Wu, M Li - Journal of Affective Disorders, 2024 - Elsevier
Background Major depressive disorder (MDD) is one of the most prevalent and debilitating
psychiatric disorders. It becomes more recognized that mitochondrial dysfunction contributes …

-Transcriptomic profiling reveals immune-related pathways involved in major depressive disorder and its phenotypic diversity

L Sforzini, A Cattaneo, M Marizzoni, V Zonca… - …, 2024 - Elsevier
Major depressive disorder (MDD) is a heterogeneous condition, hardly captured by single
biomarkers. Transcriptomic profiles are important indicators for genes and pathways …

[HTML][HTML] Integrated analysis of transcriptional changes in major depressive disorder: Insights from blood and anterior cingulate cortex

X Zhong, X Chen, Y Liu, S Gui, J Pu, D Wang, W Tao… - Heliyon, 2024 - cell.com
Background Major depressive disorder (MDD) was involved in widely transcriptional
changes in central and peripheral tissues. While, previous studies focused on single tissues …