BA CKGROUND: Transdermal therapeutic systems offer potential advantages over oral or
intravenous routes of drug administration. The purpose of this prospective study was to …

The transdermal therapeutic system (TTS) for fentanyl is a drug‐delivery system for use in
patients with chronic pain who require an opioid analgesic. A multicentre, randomized …

Background [corrected] The aim of the study was to evaluate prospectively the analgesic
efficacy, toxicity and acceptability of the transdermal fentanyl therapeutic system (TTS-F) in …

The long-term therapy of 51 patients using transdermal fentanyl was evaluated. The
transdermal therapy was performed for 158 days (range, 15–855 days). The need for …

Transdermal (TTS) fentanyl therapy has emerged as an effective alternative to the use of
oral opioids for the control of pain in certain cancer patients. These patients are those with …

This open prospective study evaluated the combination of initial dose titration with patient-
controlled analgesia (PCA) and long-term treatment with transdermal fentanyl in 50 cancer …

A multicenter study was conducted to determine the patient and physician acceptability of
transdermal fentanyl in the management of cancer-related pain. In this study, 10 cancer …

The management of pain is complex having to take into consideration patient specific
characteristics. Drug therapy should be individualized and managed based on numerous …

Transdermal fentanyl offers the advantage of providing continuous administration of a potent
opioid in the absence of needles and expensive drug-infusion pumps for the treatment of …

Alternative routes of drug delivery have particular relevance for use in chronic pain. When
the pain experience is constant or nearly constant, a continuous infusion of drug is an ideal …