Hereditary dysphasic disinhibition dementia (HDDD) describes a familial disorder
characterized by personality changes, and language and memory deficits. The …

Objective Familial autosomal dominant frontotemporal dementia with ubiquitin‐positive, tau‐
negative inclusions in the brain linked to 17q21‐22 recently has been reported to carry null …

The most common pathology in frontotemporal dementia (FTD) is tau-negative, ubiquitin-
immunoreactive (ub-ir) neuronal inclusions (FTLD-U). Recently, we identified mutations in …

Frontotemporal lobar degeneration (FTLD) refers to a focal, non-Alzheimer form of cerebral
degeneration that encompasses the distinct clinical syndromes of frontotemporal dementia …

Objective To characterize a kindred with a familial neurodegenerative disorder associated
with a mutation in progranulin (PGRN), with emphasis on the unique clinical features in this …

Frontotemporal lobar degeneration (FTLD) is a clinically, pathologically and genetically
highly complex disorder. In the last few years enormous progress has been made in …

Frontotemporal lobar degeneration is heterogeneous; cases with tau-and synuclein-
negative, ubiquitin-positive neuronal inclusions are the most common, and some have …

Mutations in the progranulin (PGRN) gene on chromosome 17 have been shown to be
responsible for one non‐tauopathy subtype of familial frontotemporal lobar degeneration …

We previously reported a kindred with three cases of dementia, in which the proband
exhibited features typical of frontotemporal dementia and parkinsonism (FTDP). An arginine …

Frontotemporal dementia (FTD) is one of the commonest forms of early-onset dementia,
accounting for up to 20% of all dementia patients. Recently, it has been shown that …