Aims Frontotemporal dementias are neuropathologically characterised by frontotemporal
lobar degeneration (FTLD). Intraneuronal inclusions of transactive response DNA‐binding …

Objective: Loss-of-function mutations in the progranulin gene (PGRN) were identified in
frontotemporal lobar degeneration (FTLD) with ubiquitin-immunoreactive neuronal …

Objective The clinical and pathologic features of hereditary dysphasic disinhibition dementia
(HDDD) are described to determine whether it is a variant of known dementias. Background …

Frontotemporal lobar degeneration is the term used to describe the non-Alzheimer clinical
syndromes of frontotemporal dementia, semantic dementia and progressive non-fluent …

We describe a case of late onset frontotemporal dementia carrying the g. 1977 1980
delCACT (Thr272fs) mutation in progranulin (GRN) gene, characterized by a positive family …

Null mutations in the progranulin gene (GRN, PGRN) were recently identified as the causal
mechanism underlying frontotemporal dementia (FTD) with ubiquitin‐positive brain …

Background Frontotemporal dementia (FTD) is predominantly a presenile disorder that is
characterised by behavioural changes and cognitive impairment, particularly in language …

RA Armstrong, D. Carter and NJ Cairns (2012) Neuropathology and Applied
Neurobiology38, 25–38 A quantitative study of the neuropathology of 32 sporadic and …

Background: Progranulin (GRN) mutations in frontotemporal dementia (FTD) have been less
frequently reported in China than in Western countries. Objective: This study reports a novel …

Frontotemporal dementia (FTD) encompasses a group of neurodegenerative disorders
characterized by cognitive and behavioral impairments. Heterozygous mutations in …