The goal of this study was to explore quantitative assessments of mineralized silk protein
biomaterial films by co-cultures of human mesenchymal stem cell-derived osteoblasts and …

The degradation of silk protein films by human mesenchymal stem cells (hMSCs),
osteoblasts and osteoclasts, cells involved in osteogenic functions in normal and diseased …

Bone mineralisation is a well-orchestrated procedure triggered by a protein-based template
inducing the nucleation of hydroxyapatite (HA) nanocrystals on the matrix. In an attempt to …

Understanding the properties and behavior of biomineralized protein-based materials at the
organic-inorganic interface is critical to optimize the performance of such materials for …

Bone repairs represent a major focus in orthopedic medicine with biomaterials as a critical
aspect of the regenerative process. However, only a limited set of biomaterials are utilized …

For tissue engineering, fabrication of appropriate biomaterials, which not only support
cellular attachment and proliferation but also direct lineage-specific differentiation of stem …

Human in vitro bone models can create the possibility for investigation of physiological bone
remodeling while addressing the principle of replacement, reduction and refinement of …

Bone (re)-generation and bone fixation strategies utilize biomaterial implants, which are
gradually replaced by autologous tissues. Ideally, these biomaterials should be …

The goals of the present study are to establish an in vitro co‐culture model of osteoblast and
osteoclast function and to quantify the resulting bone remodeling. The bone is tissue …

Osteoinductive and biodegradable composite biomaterials for bone regeneration were
prepared by combining silk fibroin with silica particles. The influence of these composite …