[HTML][HTML] SARS-CoV-2 cellular entry is independent of the ACE2 cytoplasmic domain signaling
T Karthika, J Joseph, VRA Das, N Nair, P Charulekha… - Cells, 2021 - mdpi.com
Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and-2
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
[HTML][HTML] Targeting the entry step of SARS-CoV-2: a promising therapeutic approach
J Li, P Zhan, X Liu - Signal transduction and targeted therapy, 2020 - nature.com
A very recent study published in Cell by Hoffmann and coworkers identifies the key proteins
exploited by SARS-CoV-2 to invade cells, and finds some effective therapeutic strategies …
exploited by SARS-CoV-2 to invade cells, and finds some effective therapeutic strategies …
[HTML][HTML] Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection
N Shukla, SM Roelle, VG Suzart, AM Bruchez… - PLoS …, 2021 - journals.plos.org
SARS-CoV and SARS-CoV-2 encode spike proteins that bind human ACE2 on the cell
surface to enter target cells during infection. A small fraction of humans encode variants of …
surface to enter target cells during infection. A small fraction of humans encode variants of …
[HTML][HTML] Structural and functional basis of SARS-CoV-2 entry by using human ACE2
The recent emergence of a novel coronavirus (SARS-CoV-2) in China has caused
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
[HTML][HTML] SARS-CoV-2 cell entry beyond the ACE2 receptor
SD Alipoor, M Mirsaeidi - Molecular biology reports, 2022 - Springer
Background Angiotensin-converting enzyme 2 (ACE2) is known as the major viral entry site
for SARS-CoV-2. However, viral tissue tropism and high rate of infectivity do not directly …
for SARS-CoV-2. However, viral tissue tropism and high rate of infectivity do not directly …
Cell entry mechanisms of SARS-CoV-2
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) is
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how …
[HTML][HTML] SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor
M Hoffmann, H Kleine-Weber, S Schroeder, N Krüger… - cell, 2020 - cell.com
The recent emergence of the novel, pathogenic SARS-coronavirus 2 (SARS-CoV-2) in
China and its rapid national and international spread pose a global health emergency. Cell …
China and its rapid national and international spread pose a global health emergency. Cell …
Expression pattern and function of SARS-CoV-2 receptor ACE2
R Li, C Qin - Biosafety and Health, 2021 - mednexus.org
Since the outbreak at the end of 2019, SARS-CoV-2 has been spreading around the world
for more than one year. Scientists have been intensely conducting research on this newly …
for more than one year. Scientists have been intensely conducting research on this newly …
[HTML][HTML] ACE2-independent alternative receptors for SARS-CoV-2
S Lim, M Zhang, TL Chang - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), the causative agent
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …
of coronavirus disease 2019 (COVID-19), is highly contagious and remains a major public …
[HTML][HTML] Novel sars-cov-2 receptors: asgr1 and kremen1
M Hoffmann, S Pöhlmann - Cell research, 2022 - nature.com
The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed
to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu …
to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu …