Topical recombinant human epidermal growth factor for diabetic foot ulcers: A meta-analysis of randomized controlled clinical trials

Q Yang, Y Zhang, H Yin, Y Lu - Annals of vascular surgery, 2020 - Elsevier
Diabetic foot ulcer and its complications are becoming more and more serious problems
threatening people's health. In the last decade, multiple growth factors and their combined …

Efficacy of topical recombinant human epidermal growth factor for treatment of diabetic foot ulcer: a systematic review and meta-analysis

S Yang, Z Geng, K Ma, X Sun… - The international journal …, 2016 - journals.sagepub.com
Diabetic foot ulceration is a major complication of diabetes mellitus. Recombinant human
epidermal growth factor (rhEGF) is used topically in the treatment of diabetic foot ulcers. This …

Efficacy and safety of recombinant human epidermal growth factor for diabetic foot ulcers: A systematic review and meta‐analysis of randomised controlled trials

DY Zhao, YN Su, YH Li, TQ Yu, J Li… - International Wound …, 2020 - Wiley Online Library
To evaluate the efficacy and safety of recombinant human epidermal growth factor (rhEGF)
in treating diabetic foot ulcers (DFUs), we conducted both database searches (PubMed …

Epidermal growth factor is effective in the treatment of diabetic foot ulcers: meta-analysis and systematic review

TQ Bui, QVP Bui, D Németh, P Hegyi… - International journal of …, 2019 - mdpi.com
Diabetic foot ulcers (DFUs) are one the common complications of diabetes mellitus. Many
trials were performed to evaluate the effect of recombinant human epidermal growth factor …

Efficacy of intralesional recombinant human epidermal growth factor in diabetic foot ulcers in M exican patients: A randomized double‐blinded controlled trial

R Gomez‐Villa, F Aguilar‐Rebolledo… - Wound Repair and …, 2014 - Wiley Online Library
The healing process in diabetic foot ulcer (DFU) is hindered by factors such as chronic
inflammation, defects in fibroblast function, poor angiogenesis, and lack of cell migration …

Topical epidermal growth factor spray for the treatment of chronic diabetic foot ulcers: A phase III multicenter, double-blind, randomized, placebo-controlled trial

KH Park, SH Han, JP Hong, SK Han, DH Lee… - Diabetes research and …, 2018 - Elsevier
Aims This study was conducted to evaluate the efficacy and safety of a novel spray-applied
growth factor therapy containing recombinant human epidermal growth factor (rhEGF) for the …

Intralesional injections of Citoprot‐P® (recombinant human epidermal growth factor) in advanced diabetic foot ulcers with risk of amputation

JI Fernández‐Montequín… - International Wound …, 2007 - Wiley Online Library
To investigate the efficacy and safety of recombinant human epidermal growth factor
(rhEGF) in advanced diabetic foot ulcers (DFU) A double‐blind trial was carried out to test …

Active post-marketing surveillance of the intralesional administration of human recombinant epidermal growth factor in diabetic foot ulcers

IB Yera-Alos, L Alonso-Carbonell… - BMC Pharmacology and …, 2013 - Springer
Background After several exploratory and confirmatory clinical trials, the intralesional
administration of human recombinant epidermal growth factor (hrEGF) has been approved …

[图书][B] Intralesional human recombinant epidermal growth factor for the treatment of advanced diabetic foot ulcer: from proof of concept to confirmation of the efficacy …

PA López-Saura, A del Río-Martín, B Acevedo-Castro… - 2011 - researchgate.net
Foot ulceration is among the most significant complications of diabetes. It is estimated that
15% of the diabetic patients develop ulcers at some point in their lives (Reiber, 1996). The …

[PDF][PDF] Medical practice confirms clinical trial results of the use of intralesional human recombinant epidermal growth factor in advanced diabetic foot ulcers

PA López-Saura, IB Yera-Alos… - Adv …, 2013 - pdfs.semanticscholar.org
The intralesional injection of recombinant human epidermal growth factor (rhEGF) has been
recently approved and introduced in several countries for the treatment of advanced diabetic …