Fungal infections are still threatening human health due to resistance to existing drugs,
therefore, the design and development of novel antifungal agents is to be necessary and …

Our current work is aimed at synthesizing novel derivatives of 1, 2, 3–triazolyl–indazoles,
applying docking techniques and biological evaluation in order to find active promising …

Abstract Novel 5-amino-1, 2, 4-triazole derivatives and their cyclized 1, 2, 4-triazolo [1, 5-a]
pyrimidine analogues were designed, synthesized and evaluated for their antimicrobial …

Fungal infections have become a serious threat to human health due to their high incidence
and mortality. In this study, a new set of imidazole derivatives (7a-f) were synthesized and …

The development of innovative antifungal agents is essential. Some fungicidal agents are no
longer effective due to resistance development, various side effects, and high toxicity …

Clinical needs for new antifungal agents have gradually and steadily increased with the rise
of AIDS-related mycoses, and the change in spectrum of fatal disseminated fungal …

Candidiasis is a serious public health problem that currently affects not only
immunodeficient patients with predisposing conditions, but also immunocompetent …

The azole pharmacophore is still regarded as a viable lead structure for the synthesis of
more effective antifungal agents. In this study, two novel series of imidazole derivatives …

The incidence of life-threatening fungal infections has dramatically increased for decades. In
order to develop novel antifungal agents, two series of (2 R, 3R)-1-(1H-1, 2, 4-triazol-1-yl)-2 …

An environmental friendly heterogeneous catalyst Cell-CuI-NPs was employed for the
synthesis of biologically promising 1-((1-aryl)-1H-1, 2, 3-triazol-4-yl) methyl-5-fluoroindoline …