A combination of indole-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and …
Y Nakamura, S Yogosawa, Y Izutani, H Watanabe… - Molecular cancer, 2009 - Springer
Background The chemopreventive effects of dietary phytochemicals on malignant tumors
have been studied extensively because of a relative lack of toxicity. To achieve desirable …
have been studied extensively because of a relative lack of toxicity. To achieve desirable …
Anti-cancer effects of naturally occurring compounds through modulation of signal transduction and miRNA expression in human colon cancer cells
M Kumazaki, S Noguchi, Y Yasui, J Iwasaki… - The Journal of nutritional …, 2013 - Elsevier
Much evidence indicates that various naturally occurring compounds have an anti-cancer
effect, but the detailed mechanisms are not well understood. In this study, we selected anti …
effect, but the detailed mechanisms are not well understood. In this study, we selected anti …
Genistein induces activation of the mitochondrial apoptosis pathway by inhibiting phosphorylation of Akt in colorectal cancer cells
J Qin, JA Teng, Z Zhu, JX Chen… - Pharmaceutical biology, 2016 - Taylor & Francis
Context: Genistein inhibits the proliferation and induces apoptosis of colorectal cancer cells;
however, the underling molecular mechanisms remain to be determined. Aim: The aim of …
however, the underling molecular mechanisms remain to be determined. Aim: The aim of …
Apoptosis and autophagy induction as mechanism of cancer prevention by naturally occurring dietary agents
E Mukhtar, V Mustafa Adhami, N Khan… - Current drug …, 2012 - ingentaconnect.com
Nontoxic naturally occurring compounds, especially those from dietary sources, are
receiving increasing consideration for prevention and treatment of diseases including …
receiving increasing consideration for prevention and treatment of diseases including …
[HTML][HTML] Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells
J Yang, C Pi, G Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Apigenin is a dietary flavonoid with known antioxidant and antitumor effects against several
types of cancers by promoting cell death and inducing cell cycle arrest. Apigenin also …
types of cancers by promoting cell death and inducing cell cycle arrest. Apigenin also …
Natural compounds modulate the crosstalk between apoptosis-and autophagy-regulated signaling pathways: Controlling the uncontrolled expansion of tumor cells
C Braicu, O Zanoaga, AA Zimta, AB Tigu… - Seminars in Cancer …, 2022 - Elsevier
Due to the high number of annual cancer–related deaths, and the economic burden that this
malignancy affects today's society, the study of compounds isolated from natural sources …
malignancy affects today's society, the study of compounds isolated from natural sources …
Extended treatment with physiologic concentrations of dietary phytochemicals results in altered gene expression, reduced growth, and apoptosis of cancer cells
EP Moiseeva, GM Almeida, GDD Jones… - Molecular cancer …, 2007 - AACR
Dietary phytochemicals exhibit chemopreventive potential in vivo through persistent low-
dose exposures, whereas mechanistic in vitro studies with these agents generally use a …
dose exposures, whereas mechanistic in vitro studies with these agents generally use a …
Terpenoids' anti-cancer effects: Focus on autophagy
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
Senolytic flavonoids enhance type-I and type-II cell death in human radioresistant colon cancer cells through AMPK/MAPK pathway
Simple Summary The role of autophagy and senescence in cancer resistance to ionizing
radiation as a response to genotoxic stress is still only partially explored. The flavonoids …
radiation as a response to genotoxic stress is still only partially explored. The flavonoids …
Ginkgolic acid induces interplay between apoptosis and autophagy regulated by ROS generation in colon cancer
Y Liu, B Yang, L Zhang, X Cong, Z Liu, Y Hu… - Biochemical and …, 2018 - Elsevier
Presently, developing effective anti-colon cancer drugs still remains to be important.
Ginkgolic acids (GA), as a botanical drug extracted from the seed coat of Ginkgo biloba L …
Ginkgolic acids (GA), as a botanical drug extracted from the seed coat of Ginkgo biloba L …
相关搜索
- akt phosphorylation progression of autophagy
- akt phosphorylation combination of indole
- apoptosis and autophagy colon cancer
- ginkgolic acid colon cancer
- ros generation colon cancer
- phosphorylation of akt cancer cells
- apoptosis and autophagy carcinoma cells
- modulation of autophagy cancer cells
- phosphorylation of akt apoptosis pathway
- apoptosis pathway cancer cells
- autophagy induction cancer prevention
- autophagy and apoptosis antitumor activity
- physiologic concentrations cancer cells
- extended treatment cancer cells
- antitumor activity cancer cells
- apoptosis and autophagy ginkgolic acid