Development and validation of an ELISA kit for the detection of ricin toxins from biological specimens and environmental samples

HY Chen, H Tran, LY Foo, TW Sew… - Analytical and bioanalytical …, 2014 - Springer
Ricin is a toxin that can be easily extracted from seeds of Ricinus communis plants. Ricin is
considered to be a major bio-threat as it can be freely and easily acquired in large …

Broad recognition of ricin toxins prepared from a range of Ricinus cultivars using immunochromatographic tests

P Thullier, G Griffiths - Clinical Toxicology, 2009 - Taylor & Francis
Introduction. It is extremely important that diagnosis of persons exposed to ricin be achieved
in a timely fashion for triage and appropriate treatment. A sensitive and specific …

[HTML][HTML] Rapid, sensitive and reliable ricin identification in serum samples using LC–MS/MS

L Feldberg, E Elhanany, O Laskar, O Schuster - Toxins, 2021 - mdpi.com
Ricin, a protein derived from the seeds of the castor bean plant (Ricinus communis), is a
highly lethal toxin that inhibits protein synthesis, resulting in cell death. The widespread …

Development and validation of streptavidin-biotin-based double antibody sandwich ELISA for ricin diagnosis

S Dixit, J Parashar, RK Dhaked, A Kumar… - International …, 2024 - Elsevier
Background Ricin is a potential biowarfare agent. It is a phytotoxin isolated from castor
seeds. At present there is no antidote available for ricin poisoning, patients only get …

Mass spectrometric detection of ricin and its activity in food and clinical samples

SR Kalb, JR Barr - Analytical chemistry, 2009 - ACS Publications
Ricin is a potent toxin capable of inhibiting protein synthesis and causing death or
respiratory failure. Because of its high availability and lethality, ricin is considered a likely …

[HTML][HTML] Recommended immunological assays to screen for ricin-containing samples

S Simon, S Worbs, MA Avondet, DM Tracz, J Dano… - Toxins, 2015 - mdpi.com
Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents
known. Due to its availability, toxicity, ease of production and absence of curative treatments …

[HTML][HTML] An international proficiency test to detect, identify and quantify ricin in complex matrices

S Worbs, M Skiba, J Bender, R Zeleny, H Schimmel… - Toxins, 2015 - mdpi.com
While natural intoxications with seeds of Ricinus communis (R. communis) have long been
known, the toxic protein ricin contained in the seeds is of major concern since it attracts …

Detection of residual toxin in tissues of ricin-poisoned mice by sandwich enzyme-linked immunosorbent assay and immunoprecipitation

J Men, L Lang, C Wang, J Wu, Y Zhao, PY Jia… - Analytical …, 2010 - Elsevier
This work aimed to evaluate a method to detect the residual ricin in animal tissues.
Immunoprecipitation and sandwich enzyme-linked immunosorbent assay (ELISA) were …

[PDF][PDF] Detection of ricin by comparative indirect ELISA using fluorescence probe in blood and red blood cells

S Pradhan, OM Kumar, PC Jatav, S Singh - J Med CBR Def, 2009 - academia.edu
The purpose of this study was to develop a highly sensitive and reproducible fluorescence
immunoassay (FIA) for the detection of ricin in buffer as well as in ricin spiked blood. For the …

Functional Assays for Ricin Detection

E Ezan, E Duriez, F Fenaille, F Becher - Detection of Biological Agents for …, 2010 - Springer
In this review, we provide background information on ricin structure, present available
functional assays for other toxins that are potential biothreat agents, and finish by describing …