Pathological changes in the heart or kidney can instigate the release of a cascade of
cardiorenal mediators that promote injury in the other organ. Combined dysfunction of heart …

Chronic kidney disease (CKD), the presence of kidney dysfunction and/or damage, is a
worldwide public health issue. Although CKD is independently associated with various …

Chronic kidney disease (CKD) is a great risk factor for cardiovascular disease events and
mortality, and progressively develops to the clinical phenotype called" uremic …

The combination of chronic kidney disease (CKD) and heart failure (HF) is associated with
an adverse prognosis. Although clinical studies hint at a specific bidirectional interaction …

Cardiovascular disease is a leading cause of death among patients with end stage renal
failure. Animal models have played a crucial role in teasing apart the complex pathological …

Objectives A proof of concept cross-sectional study investigating changes in myocardial
abnormalities across stages of chronic kidney disease (CKD). Characterizing noninvasive …

Background Tissue remodeling is usually dependent on the deposition of extracellular
matrix that may result in tissue stiffness and impaired myocardium contraction. Objectives …

Uremic cardiomyopathy is responsible for high morbidity and mortality rates among patients
with chronic kidney disease (CKD) or end‐stage renal disease (ESRD); however, the early …

Chronic kidney disease is associated with an increased risk for the development and
progression of cardiovascular disorders including hypertension, dyslipidemia, and coronary …

Impaired renal function with loss of nephron number in chronic renal disease (CKD) is
associated with increased cardiovascular morbidity and mortality. However, the structural …