To explain ventricular concentric and/or eccentric hypertrophy in chronic kidney disease,
past studies suggested that this was the result of increased preload and/or afterload. Using a …

Chronic kidney disease is associated with a unique cardiomyopathy, characterized by a
combination of structural and cellular remodeling, and an enhanced susceptibility to …

The interconnection of heart performance and kidney function plays an important role for
maintaining homeostasis through a variety of physiological crosstalk between these organs …

Chronic renal failure (CRF) is associated with an increased incidence of cardiovascular
diseases. Intensive research revealed a number of alterations in the heart during CRF; …

Chronic kidney disease (CKD) and cardiac insufficiency often co-exist, particularly in uremic
patients on hemodialysis (HD). The occurrence of abnormal renal function in patients with …

Background: Patients with chronic kidney disease (CKD) are at increased risk of developing
cardiac arrhythmogenesis and sudden cardiac death; however, the basis for this association …

Because of the plethora of genetic manipulations available in the mouse, we performed a
partial nephrectomy in the mouse and examined whether the phenotypical features of …

Heart failure (HF) secondary to myocardial infarction (MI) is linked to kidney complications
that comprise cellular, structural, functional, and survival indicators. However, HF research is …

Background The end stage renal disease population has a 20 fold higher incidence of
cardiovascular mortality compared to the overall population. The development of reno …

Rationale & Objective Heart-kidney crosstalk is recognized as the cardiorenal syndrome. We
examined the association of cardiac function and structure with the risk of kidney failure with …