Recently, 104 different translocations involving MLL have been described in adult and
pediatric acute leukemia, with more than 64 translocation partner genes now characterized …

Acute myeloid leukaemia (AML) is a type of heterogeneous disease derived from
haematopoietic stem cells. Cytogenetic characterisation is essential for diagnosis and …

In acute myeloid leukaemia (AML) t (8; 16)(p11; p13)/MYST3–CREBBP is a very rare
abnormality. Previous small series suggested poor outcome. We report on 59 patients with t …

Since its first description by Hillestad in 1957, acute promyelocytic leukemia (APML) has
been recognized as a distinct subtype of acute myeloid leukemia (AML) because of its …

We present a novel, rare but recurrent variant three way translocation of t (8; 21), t (8; 16;
21)(q22; q24; q22), as a primary cytogenetic abnormality, resulting in AML1/ETO fusion …

Abstract The translocation (8; 21)(q22; q22) is commonly associated with acute myeloid
leukemia (AML) M2 according to the French‐American‐British (FAB) classification. We …

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML)
characterised by the proliferation of malignant promyelocytes with mature myeloid …

Acute promyelocytic leukemia is a rare form of acute myeloid leukemia in which immature
promyelocytes abnormally proliferate in the bone marrow. In most cases, the disease is …

We present a 6-year-old girl with acute myeloid leukemia (AML)-M5, normal karyotype at the
time of diagnosis, and t (1; 3)(p36; q21) at relapse. The t (1; 3)(p36; q21) is a rare but …

Although the translocation (8; 21) is the single most common structural rearrangement
reported in acute myeloblastic leukemia (AML), it is rarely seen in AML FAB type M5. We …