Background Tumor necrosis factor-α (TNF-α) has been suggested to play a very important
role in the development and progression of hepatocellular carcinoma (HCC). Many studies …

Results A total of 23 case-control studies were investigated, involving 3,389 cases and
4,235 controls. The overall conclusion was that the A allele was more frequent in case …

Hepatocellular carcinoma (HCC) is one of the most common primary hepatic tumors, and it
is ranked as the third most common cause of cancer-linked deaths. Although the precise …

Background: Tumor necrosis factor-α (TNF-α) plays a very important role in the development
and progression of cancer. Many epidemiological studies have evaluated associations …

Tumor necrosis factor alpha (TNF-α) has been suggested to play an important role in the
development and liver cancer. TNF-α 238 G/A polymorphism was hypothesized to increase …

Background The aim of the present study was to evaluate the influence of tumor necrosis
factor-alpha (TNF-α)− 308 G> A polymorphism on hepatocellular carcinoma (HCC) risk …

Background: The genetic basis of susceptibility to hepatocellular carcinoma (HCC) is poorly
understood. Tumor necrosis factor alpha (TNF-α) is a cytokine that may act as an …

Background Research focusing on the relationship between five types of tumor necrosis
factor-alpha (TNF-α) SNPs and the risk of hepatocellular carcinoma (HCC) were still …

Background Studies investigating the associations between tumor necrosis factor-alpha
(TNFA) polymorphisms and hepatocellular carcinoma (HCC) risk report conflicting results …

Results The overall results suggested that the TNFA-308 AA and AG variant genotypes were
associated with a significantly increased risk of HCC in different genetic models …