BACKGROUND: The underlying genetic factors for the development and progression of
hepatocellular carcinoma (HCC) are largely unknown. TNFα is a well characterized …

To assess the contribution of tumor necrosis factor $(TNF){\beta} $+ 252 polymorphisms to
risk and prognosis of hepatocellular carcinoma (HCC), we enrolled 150 pairs of sex-and age …

Abstract Background and Aims: Tumor necrosis factor-α (TNF-α) is a cytokine that may act as
an endogenous tumor promoter. A genetic polymorphism of TNF-α at position− 308 of the …

TNF-α is a potential proinflammatory cytokine that plays an important role in the
pathogenesis of liver cirrhosis. We investigated a possible association between TNF-α …

The single nucleotide polymorphisms (SNPs) within the tumor necrosis factor-α (TNF-α)
gene promoter region have been reported to be associated with susceptibility to various …

Background. The genetic basis of susceptibility to hepatocellular carcinoma (HCC) is poorly
understood. Genomic DNA was available from 98 patients with HCC, 77 familial controls, 97 …

Objectives. To investigate the potential association of tumor necrosis factor‐α T‐857C
polymorphism with susceptibility to the five common malignant tumors. Materials and …

Background: Hepatitis B virus (HBV) is a key factor for hepatocellular carcinoma (HCC).
About 350 million people are affected by chronic infection which is related to the rapid …

Cirrhosis is an active hepatic inflammation process of the liver considered as the serious
phase of different liver injuries. Epidemiological studies have evaluated the possible …

Epidemiological studies have evaluated the association between tumour necrosis factor
alpha (TNF-α)-308G/A and (TNF-α)-238G/A polymorphisms, and the risk of autoimmune liver …