Host defense peptides: front-line immunomodulators
SC Mansour, OM Pena, REW Hancock - Trends in immunology, 2014 - cell.com
Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now
widely recognized for their multifunctional roles in both the innate and adaptive immune …
widely recognized for their multifunctional roles in both the innate and adaptive immune …
The immunology of host defence peptides: beyond antimicrobial activity
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
sequences that are produced by various cells and tissues in all complex life forms. HDPs …
Host defense peptides and their antimicrobial-immunomodulatory duality
L Steinstraesser, U Kraneburg, F Jacobsen… - Immunobiology, 2011 - Elsevier
Host defence peptides (HDPs) are short cationic molecules produced by the immune
systems of most multicellular organisms and play a central role as effector molecules of …
systems of most multicellular organisms and play a central role as effector molecules of …
Multifunctional cationic host defence peptides and their clinical applications
ATY Yeung, SL Gellatly, REW Hancock - Cellular and Molecular Life …, 2011 - Springer
With the rapid rise in the emergence of bacterial strains resistant to multiple classes of
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …
antimicrobial agents, there is an urgent need to develop novel antimicrobial therapies to …
Strategies in translating the therapeutic potentials of host defense peptides
The golden era of antibiotics, heralded by the discovery of penicillin, has long been
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …
Antimicrobial host defence peptides: immunomodulatory functions and translational prospects
AM van der Does, PS Hiemstra… - … Peptides: Basics for …, 2019 - Springer
Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …
wide range of activities contributing to immune responses and resolution of infections …
Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
Cationic host defence peptides: multifaceted role in immune modulation and inflammation
KY Choi, LNY Chow, N Mookherjee - Journal of innate immunity, 2012 - karger.com
Host defence peptides (HDPs) are innate immune effector molecules found in diverse
species. HDPs exhibit a wide range of functions ranging from direct antimicrobial properties …
species. HDPs exhibit a wide range of functions ranging from direct antimicrobial properties …
[HTML][HTML] Reassessing the host defense peptide landscape
Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …
Exploring the pharmacological potential of promiscuous host-defense peptides: from natural screenings to biotechnological applications
ON Silva, KCL Mulder, AEAD Barbosa… - Frontiers in …, 2011 - frontiersin.org
In the last few years, the number of bacteria with enhanced resistance to conventional
antibiotics has dramatically increased. Most of such bacteria belong to regular microbial …
antibiotics has dramatically increased. Most of such bacteria belong to regular microbial …