Many protein factors are required for mRNA biogenesis and nuclear export, which are
central to the eukaryotic gene expression program. It is unclear, however, whether all factors …

Assembly of Export-Competent mRNP: It's All about Being Connected: Molecular Cell Skip to
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Nuclear processing of mRNAs and mRNA export to the cytoplasm are integral steps in gene
expression. In the nucleus, newly transcribed mRNAs undergo multiple processing steps …

Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well
coordinated processing steps, resulting in the formation of an export competent …

Following transcription and processing, eukaryotic mRNAs are exported from the nucleus to
the cytoplasm for translation. Here we present evidence that mRNAs are targeted for nuclear …

Regulation of gene expression can occur at many different levels. One important step in the
gene expression process is the transport of mRNA from the nucleus to the cytoplasm. In …

MRNA export is an indispensable step during the complex process of eukaryotic gene
expression: the mRNA, created by RNA polymerase II in the nucleus, has to be trans‑ported …

In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

Fully processed mRNAs are exported to the cytoplasm where they direct protein synthesis.
Export of mRNAs is mediated by a conserved heterodimeric transport receptor (known as …

Three independent pathways of nuclear import have so far been identified in yeast, each
mediated by cognate nuclear transport factors, or karyopherins. Here we have characterized …