[HTML][HTML] Precision medicine approaches to overcome resistance to therapy in head and neck cancers

S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is the sixth most incident cancer
worldwide. More than half of HNSCC patients experience locoregional or distant relapse to …

Targeted therapy in head and neck cancer

SK Kundu, M Nestor - Tumor Biology, 2012 - Springer
Head and neck squamous cell carcinoma (HNSCC) of multi-factorial etiopathogenesis is
rising worldwide. Treatment-associated toxicity problems and treatment failure in advanced …

[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

An update: emerging drugs to treat squamous cell carcinomas of the head and neck

YS Lee, DE Johnson, JR Grandis - Expert opinion on emerging …, 2018 - Taylor & Francis
Introduction: Subsequent to the 2006 FDA approval of cetuximab, a variety of molecular
targeting agents have been evaluated in head and neck squamous cell carcinoma …

Molecular targeted therapy of head and neck cancer: review and clinical development challenges

C Le Tourneau, S Faivre, LL Siu - European journal of cancer, 2007 - Elsevier
Recently, new targets have been identified in head and neck squamous cell carcinomas
(HNSCC) as playing key roles in tumour proliferation and metastases. The first target that …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Targeted therapies for squamous cell carcinoma of the head and neck: current knowledge and future directions

S Schmitz, KK Ang, J Vermorken, R Haddad… - Cancer treatment …, 2014 - Elsevier
Despite progress in the therapeutic management of patients with squamous cell carcinoma
of the head and neck (SCCHN), the mortality rate of patients presenting with advanced …

Emerging drugs to treat squamous cell carcinomas of the head and neck

C Fung, JR Grandis - Expert opinion on emerging drugs, 2010 - Taylor & Francis
Importance of the field: Head and neck squamous cell carcinoma (HNSCC) is the eighth
leading cause of cancer death worldwide. Despite advances in surgery and chemoradiation …

State-of-the-art and emerging treatment options in the management of head and neck cancer: news from 2013

N Denaro, EG Russi, V Adamo, MC Merlano - Oncology, 2014 - karger.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cause of
cancer death worldwide. Its treatment is complex and evolving. In general, early-stage …

Emerging drugs for head and neck cancer

Y Wen, JR Grandis - Expert opinion on emerging drugs, 2015 - Taylor & Francis
Introduction: Despite improvements in treatment, survival rates of head and neck squamous
cell carcinoma (HNSCC) are stagnant. The existing chemotherapeutic agents are non …