Epigenetics is a molecular phenomenon that pertains to heritable changes in gene
expression that do not involve changes in the DNA sequence. Epigenetic modifications in a …

Evidence is emerging that several diseases and behavioral pathologies result from defects
in gene function. The best-studied example is cancer, but other diseases such as …

Epigenetics refers to heritable molecular determinants of phenotype independent of DNA
sequence. Epigenetic features include DNA methylation, histone modifications, non-coding …

Epigenetic alterations are considered to be very influential in both the normal and disease
states of an organism. These alterations include methylation, acetylation, phosphorylation …

Alterations in the genome and the epigenome are common in most cancers. Changes in
epigenetic signatures, including aberrant DNA methylation and histone deacetylation, are …

Epigenetic processes that modulate gene expression but do not involve DNA sequence
changes can have a major impact on disease development, and perhaps the most important …

Epigenetic control of gene expression occurs at two distinct levels: DNA methylation and
histone modification. Over the past 10 years, the discovery of epigenetic targets has …

Heritable changes in gene expression that do not involve coding sequence modifications
are referred to as “epigenetic”. Epigenetic mechanisms principally include DNA methylation …

Epigenetic gene silencing is a hallmark of cancer cells. Two important types of epigenetic
changes are DNA methylation and histone modification. These modifications are catalysed …

Epigenetic modifications such as histone post-transcriptional modifications, DNA
methylation, and non-protein-coding RNAs organize the DNA in the nucleus of eukaryotic …