Barley, wheat, rice and maize provide the bulk of human nutrition and have extensive
industrial use as agricultural products. The genomes of these crops each contains> 40,000 …

The central dogma of molecular biology describes the flow of genetic information from DNA
to RNA and to proteins in living biological systems. Newly emerging technologies are being …

The discovery of biochemical and cellular functions of unannotated gene products begins
with a database search of proteins with structure/sequence homologues based on known …

One hundred years ago, we knew very little about biological macromolecules and had no
tools available to study their structure. Structural biology is now a mature science. New …

The large-scale genome sequencing projects present tremendous new opportunities for
structural biology and molecular biophysics. This explosion of biological information …

Visualization tools for biological data are often limited in their ability to interactively integrate
data at multiple scales. These computational tools are also typically limited by two …

The fundamental discovery that the amino acid sequence of a protein contains the full
information specifying its native, three-dimensional conformation marked the beginning of …

The intracellular level of a protein is dependent on both its rate of synthesis and its rate of
degradation. Thus, differential regulation of protein stability represents a potential …

Protein Folding: An unfolding story: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …

The structure-function paradigm claims that a specific function of a protein is determined by
its unique and rigid three-dimensional (3D) structure. Thus, following its biosynthesis on the …