Background Individuals who had cancer in childhood are at higher risk of developing bone
cancer than any other type of second primary cancer. Purpose Using the population-based …

Studies to determine the etiology of osteosarcoma involve epidemiologic and environmental
factors and genetic impairments. Factors related to patient characteristics include age …

We estimated the risk of subsequent bone cancer among 9170 patients who had survived
two or more years after the diagnosis of a cancer in childhood. As compared with the …

Osteosarcoma is the most frequent second primary cancer occurring during the first 20 years
following treatment for a solid cancer in childhood. Using a cohort study of children treated …

[en] The study of long-term effects of therapy for childhood cancer is important for several
reasons. An increasing proportion of children are now cured of their cancer and can expect …

The risk of leukemia was evaluated in 9,170 2-or-more-year survivors of childhood cancer in
the 13 institutions of the Late Effects Study Group. Secondary leukemia occurred in 22 …

In a search for etiologic clues to primary bone cancer in childhood, we examined 1,532
death certificates of all children in the United States dying from these neoplasms, 1960–66 …

Abstract Information on 16,193 infants delivered in Great Britain in one week of April, 1970
was collected by midwives at the birth and during the first 7 days of life. Using multiple …

Of a cohort of 634 children treated from 1942 to 1969 at the Gustave Roussy Institute for a
first cancer and alive 5 years after treatment, 32 later developed second malignant …

A new malignancy was diagnosed in 19 of 414 long‐term survivors of cancer in childhood.
All but two lesions were attributable to prior radiotherapy; eight were successfully treated …