Lessons from the past and charting the future of marine natural products drug discovery and chemical biology
WH Gerwick, BS Moore - Chemistry & biology, 2012 - cell.com
Marine life forms are an important source of structurally diverse and biologically active
secondary metabolites, several of which have inspired the development of new classes of …
secondary metabolites, several of which have inspired the development of new classes of …
Drugs from the oceans: Marine natural products as leads for drug discovery
KH Altmann - Chimia, 2017 - ojs.chimia.ch
The marine environment harbors a vast number of species that are the source of a wide
array of structurally diverse bioactive secondary metabolites. At this point in time, roughly …
array of structurally diverse bioactive secondary metabolites. At this point in time, roughly …
A renaissance in marine pharmacology: from preclinical curiosity to clinical reality
KB Glaser, AMS Mayer - Biochemical pharmacology, 2009 - Elsevier
Marine pharmacology, the pharmacology of marine natural products, has been for some
time more associated with marine natural products chemistry rather than mainstay …
time more associated with marine natural products chemistry rather than mainstay …
Unlocking the potential of marine biodiscovery
The tremendous diversity of life in the ocean has proven to be a rich source of inspiration for
drug discovery, with success rates for marine natural products up to 4 times higher than …
drug discovery, with success rates for marine natural products up to 4 times higher than …
Advances in exploring the therapeutic potential of marine natural products
Marine natural products represent novel and diverse chemotypes that serve as templates for
the discovery and development of therapeutic agents with distinct mechanisms of action …
the discovery and development of therapeutic agents with distinct mechanisms of action …
[PDF][PDF] Marine natural products as sources of novel scaffolds: Achievement and concern
DX Kong, YY Jiang, HY Zhang - Drug discovery today, 2010 - academia.edu
From past to present, drug discovery has been tightly coupled with natural products. Not only
were traditional medicines composed of natural agents, but also a large proportion ($50%) …
were traditional medicines composed of natural agents, but also a large proportion ($50%) …
Drugs and cosmetics from the sea
A Kijjoa, P Sawangwong - Marine Drugs, 2004 - mdpi.com
The marine environment is a rich source of both biological and chemical diversity. This
diversity has been the source of unique chemical compounds with the potential for industrial …
diversity has been the source of unique chemical compounds with the potential for industrial …
Marine natural products: a new wave of drugs?
R Montaser, H Luesch - Future medicinal chemistry, 2011 - Taylor & Francis
The largely unexplored marine world that presumably harbors the most biodiversity may be
the vastest resource to discover novel 'validated'structures with novel modes of action that …
the vastest resource to discover novel 'validated'structures with novel modes of action that …
The marine biodiscovery pipeline and ocean medicines of tomorrow
Marine organisms possess the capacity to produce a variety of unique and biologically
potent natural products for treating human diseases, many of which are currently …
potent natural products for treating human diseases, many of which are currently …