Pulmonary immune responses to Aspergillus fumigatus in rats

I Mirkov, AAM El-Muzghi, J Djokic, M Ninkov… - Biomedical and …, 2014 - Elsevier
Objective To evaluate immunologic mechanisms underlying Aspergillus fumigatus
pulmonary infections in immunocompetent Dark Agouti (DA) and Albino Oxford (AO) rats …

Interaction of airway epithelial cells (A549) with spores and mycelium of Aspergillus fumigatus

Z Zhang, R Liu, JA Noordhoek, HF Kauffman - Journal of Infection, 2005 - Elsevier
OBJECTIVE: To study the interaction of airway epithelial cell line A549 with fragments of
mycelium, spores of Aspergillus fumigatus in vitro and to determine if toll-like receptors …

Regional cytokine responses to pulmonary aspergillosis in immunocompetent rats

AAM El-Muzghi, I Mirkov, J Djokic, AP Aleksandrov… - Immunobiology, 2013 - Elsevier
Rat models of pulmonary aspergillosis are used widely in diagnostic studies and in
exploring antifungal therapeutic modalities, but there is lack of data concerning antifungal …

Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis

EK Rødland, T Ueland, S Bjørnsen, EL Sagen… - BMC Infectious …, 2012 - Springer
Background The purpose of this study was to investigate mediators of inflammation and
haemostasis in patients with chronic necrotizing pulmonary aspergillosis (CNPA), a locally …

Effects of Aspergillus fumigatus Conidia on Apoptosis and Proliferation in an In Vitro Model of the Lung Microenvironment

H Kushima, T Tsunoda, T Matsumoto, Y Kinoshita… - Microorganisms, 2021 - mdpi.com
Background/Aim: Aspergillus is often detected in respiratory samples from patients with
chronic respiratory diseases, including pulmonary fibrosis, suggesting that it can easily …

Dexamethasone and cyclosporin A modulation of cytokine expression and specific antibody synthesis in an allergic bronchopulmonary aspergillosis murine model

JM Wang, HW Chu, M Bosse… - European journal of …, 1996 - Wiley Online Library
We previously demonstrated that, in C57B1/6 mice, cyclosporin A enhanced and
dexamethasone inhibited the Aspergillus fumigatus‐induced pulmonary eosinophilia and …

Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells

N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …

Kinetic host defense of the mice infected with Aspergillus Fumigatus

H Su, C Li, Y Wang, Y Li, L Dong, L Li, J Zhu… - Future …, 2019 - Future Medicine
Aim: Aspergillus fumigatus is one of the most common opportunistic fungi that can cause
invasive infection. To profile the kinetic variation of immune cells and cytokines after …

[HTML][HTML] Pre-exposure with extracellular vesicles from Aspergillus fumigatus attenuates inflammatory response and enhances fungal clearance in a murine model …

JAM Souza, ILS Gurgel, NLSO Malacco… - Frontiers in Cellular …, 2022 - frontiersin.org
Aspergillus fumigatus is a ubiquitous and saprophytic filamentous fungus and the main
etiologic agent of aspergillosis. Infections caused by A. fumigatus culminates in a strong …

Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4

M Dubourdeau, R Athman, V Balloy… - The Journal of …, 2006 - journals.aai.org
Aspergillus fumigatus causes invasive aspergillosis in immunosuppressed patients. In the
immunocompetent host, inhaled conidia are cleared by alveolar macrophages. The …