Suppressive effects of Aspergillus fumigatus culture filtrates on human alveolar macrophages and polymorphonuclear leucocytes

T Murayama, R Amitani, Y Ikegami… - European …, 1996 - Eur Respiratory Soc
Aspergillus spp., especially A. fumigatus (Af) can colonize the airways and the lungs with
localized underlying conditions and further invade the surrounding lung tissues, even in …

Kinetic Study of Host Defense and Inflammatory Response to Aspergillus fumigatus in Steroid-Induced Immunosuppressed Mice

M Duong, N Ouellet, M Simard… - The Journal of …, 1998 - academic.oup.com
The sequential pathogenesis of pulmonary aspergillosis was studied and the role of
inflammatory cytokines in host response to Aspergillus fumigatus was characterized in …

Combination therapy with micafungin and amphotericin B for invasive pulmonary aspergillosis in an immunocompromised mouse model

Y Nagasaki, Y Eriguchi, Y Uchida… - Journal of …, 2009 - academic.oup.com
Objectives Antifungal monotherapy with polyenes, azoles or echinocandins is not always
effective for invasive pulmonary aspergillosis (IPA). The main purpose of this study was to …

Expression profile analysis reveals that Aspergillus fumigatus but not Aspergillus niger makes type II epithelial lung cells less immunological alert

N Escobar, ID Valdes, EM Keizer, SR Ordonez… - BMC genomics, 2018 - Springer
Background Aspergillus fumigatus is the main causative agent of aspergillosis. Infections
rarely occur in immunocompetent individuals, indicating efficient clearance of conidia by …

Development of a novel inhalational model of invasive pulmonary aspergillosis in rats and comparative evaluation of three biomarkers for its diagnosis

S Ahmad, AA Al-Shaikh, Z Khan - PloS one, 2014 - journals.plos.org
Aspergillus fumigatus, a thermotolerant fungus, is the main causative agent of invasive
pulmonary aspergillosis (IPA) in immunocompromised patients that is associated with high …

Suppression of Epithelial Signal Transducer and Activator of Transcription 1 Activation by Extracts of Aspergillus fumigatus

B Bhushan, T Homma, JE Norton, Q Sha… - American journal of …, 2015 - atsjournals.org
Aspergillus fumigatus (AF) is often pathogenic in immune-deficient individuals and can
cause life-threatening infections such as invasive aspergillosis. The pulmonary epithelial …

Effects of Aspergillus fumigatusculture filtrate on antifungal activity of human phagocytes in vitro

T Murayama, R Amitani, Y Ikegami, R Kawanami… - Thorax, 1998 - thorax.bmj.com
BACKGROUND Aspergillus fumigatus can colonise the airways and the lungs with localised
underlying conditions and occasionally invade the surrounding lung tissues even in subjects …

Innate and Adaptive Immune Responses Induced by Aspergillus fumigatus Conidia and Hyphae

Y Luo, F Liu, L Deng, J Xu, Q Kong, Y Shi, H Sang - Current Microbiology, 2023 - Springer
Previous research indicated that hyphae of Aspergillus fumigatus (A. fumigatus) rather than
conidia could successfully build a pulmonary aspergillosis model in immunocompetent …

Liposomal amphotericin b fosters the corticosteroids' anti-inflammatory effect on murine allergic bronchopulmonary aspergillosis model airways

C Fukushima, H Matsuse, Y Obase, S Fukahori… - Inflammation, 2019 - Springer
Fungus is an antigen for bronchial asthma causing allergic bronchopulmonary mycosis
(ABPM). As a therapy other than corticosteroids, itraconazole (ITCZ) is known to suppress …

Exposure to Aspergillus fumigatus spores induces chemokine expression in mouse macrophages

L Pylkkänen, H Gullstén, ML Majuri, U Andersson… - Toxicology, 2004 - Elsevier
Inhalation of fungal spores may cause inflammation and respiratory diseases, such as
bronchitis, allergic alveolitis, and asthma. Alveolar macrophages provide the first line of …