Repeated inhalation of airborne conidia derived from the fungus Aspergillus fumigatus (Af)
can lead to a severe eosinophil‐dominated inflammatory condition of the lung termed …

Among immunologically normal hosts, patients with chronic obstructive pulmonary disease
(COPD) are considered to be at high risk of invasive pulmonary aspergillosis (IPA), and …

Invasive aspergillosis (IA) is a severe infection that commonly occurs in
immunocompromised patients after hematopoietic stem cell transplantation (HSCT). The …

The ubiquitous fungus Aspergillus fumigatus is associated with chronic diseases such as
invasive pulmonary aspergillosis in immunosuppressed patients and allergic …

Bronchial epithelial cells (BEC) play a crucial role in innate immunity against inhaled fungi.
Indeed, in response to microorganisms, BEC synthesize proinflammatory cytokines involved …

Background. Until now, there have been no objective criteria to determine the activity of
chronic pulmonary aspergillosis (CPA). This study aims to analyze the correlation between …

Objective To study the therapeutic effect of interleukin-2 (IL-2) and interleukin-12 (IL-12) with
and without amphotericin B on pulmonary fungal infection of mice. Methods A mouse model …

Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Candida albicans infection-induced acute lung injury is one of the most prevalent diseases
in immunosuppressive individual. Nevertheless, the mechanism by which Candida albicans …

Invasive pulmonary aspergillosis (IPA) is a life-threatening disease of immunocompromised
patients that requires aggressive therapy. Detection of the disease and monitoring of the …