[HTML][HTML] Bleeding phenotype in nonsevere hemophilia by International Society on Thrombosis and Haemostasis bleeding assessment tool, bleeding frequency, and …

J Rejtő, D Kraemmer, E Grilz, O Königsbrügge… - Research and Practice …, 2023 - Elsevier
Background Although the phenotype of severe hemophilia has been well studied, there are
still knowledge gaps in nonsevere hemophilia. Objectives The objective of this study was to …

The bleeding phenotype in people with nonsevere hemophilia

FR Kloosterman, AF Zwagemaker, CN Bagot… - Blood …, 2022 - ashpublications.org
Detailed information on the onset, frequency, and severity of bleeding in nonsevere
hemophilia is limited. We aimed to assess the bleeding phenotype of persons with …

Patients with moderate hemophilia A and B with a severe bleeding phenotype have an increased burden of disease

MJA Verhagen, EC van Balen, NMA Blijlevens… - Journal of thrombosis …, 2024 - Elsevier
Background Patients with moderate hemophilia express varying bleeding phenotypes.
Objectives To assess the burden of disease in patients with moderate hemophilia and a mild …

[HTML][HTML] Severe hemophilia with mild bleeding phenotype: molecular characterization and global coagulation profile

E Santagostino, ME Mancuso, A Tripodi… - Journal of Thrombosis …, 2010 - Elsevier
Background: Patients with severe hemophilia may show very varied bleeding tendencies,
and the reasons for this heterogeneous clinical expression are unclear. The factor VIII/FIX …

Factors that influence the bleeding phenotype in severe hemophilic patients

P Rendo, F Shafer, JM Korth-Bradley… - Blood Coagulation & …, 2013 - journals.lww.com
Hemophilia A and B are rare, X-linked bleeding disorders resulting from a partial or total
deficiency of functionally active coagulation factor VIII or factor IX, respectively. Endogenous …

Bleeding risk in hemophilia A and B carriers: comparison of factor levels determined using chronometric and chromogenic assays

D Chiffré-Rakotoarivony, I Diaz-Cau… - Blood Coagulation & …, 2024 - journals.lww.com
Objective The objectives of this study were to describe the bleeding phenotype in HAC and
HBC using the standardized Tosetto bleeding score (BS); to determine whether the BS …

Bleeding phenotype of patients with moderate haemophilia A and B assessed by thromboelastometry and thrombin generation

RJ Måseide, E Berntorp, V Nummi, R Lassila… - …, 2021 - Wiley Online Library
Introduction Predicting the bleeding phenotype is crucial for the management of patients
with moderate haemophilia. Global coagulation assays evaluate haemostasis more …

[HTML][HTML] Variability in Bleeding Pattern of Severe Hemophilia.

K van Dijk, K Fischer, JG van der Bom… - Blood, 2004 - Elsevier
Introduction The aim of this study was to describe variability in bleeding pattern in a single
center cohort of severe hemophilia patients treated with prophylaxis. Methods At the Van …

Descriptive analysis of bleeding symptoms in haemophilia carriers enrolled in the ATHNdataset

J Puetz, D Cheng - Haemophilia, 2021 - Wiley Online Library
Background Several studies have reported that haemophilia carriers have a bleeding
tendency independent of factor activity. However, investigations have been fraught with …

Evaluation of ISTH-BAT as a predictor for factor deficiency in haemophilia carriers: a single-centre experience

ME Carter-Febres, MY Lim - Blood Coagulation & Fibrinolysis, 2021 - journals.lww.com
In recent years, bleeding assessment tools (BATS) have been widely adopted into routine
clinical practice to identify and standardize the severity of bleeding symptoms experienced …