Recent technological advances have rapidly expanded our understanding of CHD genetics,
and support the applicability to the clinical domain in both sporadic and inherited disease …

The genetic mechanisms underlying congenital heart disease (CHD) are complex and
remain incompletely understood. The majority of patients with CHD have an isolated heart …

Congenital heart disease (CHD) is the most common congenital malformation and the
leading cause of mortality therein. Genetic etiologies contribute to an estimated 90% of CHD …

Congenital heart disease (CHD) is the most common major congenital anomaly with an
incidence of∼ 1% of live births and is a significant cause of birth defect–related mortality …

Congenital heart disease is the most common birth defect, and because of major advances
in medical and surgical management, there are now more adults living with congenital heart …

Congenital heart defects (CHD) are the most common congenital problems in neonates. The
basis for CHD is multifactorial, involving genetic and environmental components. The …

Our understanding of the genetics of congenital heart disease (CHD) is rapidly expanding;
however, many questions, particularly those relating to sporadic forms of disease, remain …

Background This review discusses the incidence and importance of congenital heart
disease (CHD), the reasons that investigation of causative mechanisms for human CHD has …

An intriguing question is why the mutations identified in this study cause cardiac-specific
defects. The genes pinpointed function in all cell types and broadly regulate gene …

Congenital heart disease (CHD) is the most common congenital anomaly in newborn
babies. Cardiac malformations have been produced in multiple experimental animal …