The habitat in which proteins exert their function contains up to 400 g/L of macromolecules,
most of which are proteins. The repercussions of this dense environment on protein …

The malleability of intrinsically disordered proteins (IDPs) has generated great interest in
understanding how their conformations respond to crowded cellular environments …

Macromolecular crowding influences protein mobility and stability in vivo. A precise
description of the crowding effect on protein thermal stability requires the estimate of the …

It is well-known that crowded environments affect the stability of proteins, with strong
biological and biotechnological implications; however, beyond this, crowding is also …

The interior of a cell is a highly packed environment that can be occupied up to 40% by
different macromolecules. Such crowded media influence different biochemical processes …

Proteins fold and function inside cells which are environments very different from that of
dilute buffer solutions most often used in traditional experiments. The crowded milieu results …

The cell is a crowded environment where a relevant fraction of the available space is
occupied by proteins, nucleic acids, and metabolites. Here we discuss recent advancements …

Macromolecular crowding has profound effects on the mobility of proteins, with strong
implications on the rates of intracellular processes. To describe the dynamics of crowded …

Inside the living cell is inherently crowded with proteins and other macromolecules. Thus, it
is indispensable to take into account various interactions between the protein and other …

Due to their conformational malleability, intrinsically disordered proteins (IDPs) are
particularly susceptible to influences of crowded cellular environments. Here we report a …