Ultra-low dosage regimen of rituximab in autoimmune blistering skin conditions

M Alaibac - Frontiers in immunology, 2018 - frontiersin.org
Rituximab is a chimeric human-mouse monoclonal anti-CD20 antibody initially developed to
treat B cell lymphoproliferative disorders (1). It is now increasingly being used for the …

Rituximab in treatment-resistant autoimmune blistering skin disorders

E Schmidt, EB Bröcker, M Goebeler - Clinical Reviews in Allergy & …, 2008 - Springer
Autoimmune blistering diseases are associated with autoantibodies to desmosomal
(pemphigus group) or hemidesmosomal proteins (autoimmune subepidermal blistering …

Treatment update of autoimmune blistering diseases

K Kridin, C Ahn, WC Huang, A Ansari… - Dermatologic …, 2019 - derm.theclinics.com
The aim of the treatment in autoimmune blistering diseases (AIBDs) is to induce and
maintain remission, which clinically corresponds to the cessation of new vesicle formation …

Rituximab therapy in patients with bullous pemphigoid: a retrospective study of 20 patients

M Polansky, R Eisenstadt, T DeGrazia, X Zhao… - Journal of the American …, 2019 - Elsevier
Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease
requiring treatment with immunosuppressive medications; however, finding a therapy that …

Where does rituximab fit in the treatment of autoimmune mucocutaneous blistering skin disease?

R Nigam, J Levitt - Journal of Drugs in Dermatology: JDD, 2012 - europepmc.org
We propose rituximab as a first-line therapy for pemphigus vulgaris and steroid-dependent
bullous pemphigoid with or without systemic steroids. A brief review of the literature …

Sustained clinical response to rituximab in a case of life-threatening overlap subepidermal autoimmune blistering disease

Y Li, JB Foshee, RD Sontheimer - Journal of the American Academy of …, 2011 - Elsevier
The conventional treatment for the autoimmune bullous skin diseases is broad-spectrum
immunosuppressive regimen typically combining systemic corticosteroids with adjuvant …

Rituximab for treatment-refractory pemphigus and pemphigoid: a case series of 17 patients

M Kasperkiewicz, I Shimanovich, RJ Ludwig… - Journal of the American …, 2011 - Elsevier
BACKGROUND: Rituximab has been increasingly used in autoimmune blistering
dermatoses, mainly in pemphigus. However, only a few larger case series are available on …

Rituximab in refractory autoimmune bullous diseases

E Schmidt, N Hunzelmann, D Zillikens… - Clinical and …, 2006 - academic.oup.com
Treatment of autoimmune blistering diseases consists of systemic glucocorticosteroids
usually in combination with additional immunosuppressants such as azathioprine and …

The emerging role of rituximab in autoimmune blistering diseases

AR Ahmed, S Shetty - American Journal of Clinical Dermatology, 2015 - Springer
Rituximab is a chimeric monoclonal antibody that selectively binds to the CD20 molecule on
B cells, resulting in their lysis. In autoimmune blistering diseases, the auto-antibody …

Low‐dose rituximab and concurrent adjuvant therapy for pemphigus: Protocol and single‐centre long‐term review of nine patients

AJ Robinson, M Vu, GA Unglik… - Australasian Journal …, 2018 - Wiley Online Library
Pemphigus is an autoimmune B‐cell mediated blistering disease associated with significant
morbidity and mortality. Rituximab has proven effective for the treatment of steroid‐refractory …