Cholesteryl ester transfer protein (CETP) catalyzes the transfer of cholesteryl ester from high-
density lipoprotein (HDL) to apolipoprotein B-containing lipoproteins in exchange for …

Elevated low-density lipoprotein-cholesterol (LDL-C) and reduced high-density lipoprotein-
cholesterol (HDL-C) are major risk factors for the development of cardiovascular disease …

Background: Not only hypercholesterolemia, but also low levels of high-density lipoprotein
cholesterol is a critical risk factor for atherosclerosis-related disease. Therefore, there has …

Epidemiologic studies have shown that the concentration of high-density lipoprotein
cholesterol (HDL-C) is a strong, independent, inverse predictor of coronary heart disease …

Objective—The ability of the potent cholesteryl ester transfer protein (CETP) inhibitor
torcetrapib (CP-529,414) to raise high-density lipoprotein cholesterol (HDL-C) levels in …

Cholesteryl ester transfer protein (CETP) plays an important role in cholesterol metabolism
because it is responsible for the transfer of cholesteryl esters from high-density lipoprotein …

Cholesteryl ester transfer protein (CETP) inhibitors are currently being investigated because
of their ability to increase high-density lipoprotein cholesterol levels. In various metabolic …

Among the noteworthy recent stories in the management and prevention of atherosclerotic
cardiovascular disease (CVD) is the saga of the development of pharmacological inhibitors …

In almost 30 years since the introduction of HMG-CoA reductase inhibitors (statins), no other
class of lipid modulators has entered the market. Elevation of high-density lipoprotein …

Introduction: Inhibition of cholesteryl ester transfer protein (CETP) has the ability to increase
high-density lipoprotein (HDL)-cholesterol levels and potentially reduce cardiovascular risk …