OBJECTIVE: To investigate whether intima-media thickness (IMT) of the common carotid
artery (CCA), an early marker of asymptomatic atherosclerosis, is significantly and …

Background—The mechanisms by which obesity increases the risk of atherosclerotic
cardiovascular disease (CVD) are poorly understood. In experimental models, leptin, a …

Background The adipocyte-derived hormone leptin plays a key role in the regulation of
appetite and body weight. Recent studies have suggested that leptin is also involved in the …

BACKGROUND AND AIM: Leptin, an adipocyte-derived protein, regulating food intake and
metabolism has been implicated in the development of coronary heart disease. We have …

OBJECTIVE: To study the relationship of leptin concentrations with indices of obesity, fasting
insulin, insulin resistance and lipid profiles (total cholesterol, low density lipoprotein (LDL) …

Aims The aim of this study was to evaluate the relationship of obesity, leptin, insulin
resistance and C‐reactive protein (CRP) with coronary heart disease (CHD) risk factors in …

To the Editor: Diabetic metabolic abnormalities induce vascular dysfunction that predisposes
diabetic patients to atherosclerosis [1]. Complications of atherosclerosis cause much of the …

Leptin, a 167-amino acid peptide hormone produced by white adipose tissue, is primarily
involved in the regulation of food intake and energy expenditure. Leptin receptors are …

Objective Previous studies on humans have reported higher leptin levels in women than in
men, independent of body fat, and leptin has been correlated with insulin resistance in men …

Leptin is an adipose tissue-derived hormone shown to be related to metabolic, inflammatory,
and hemostatic factors involved in hypertension development. Animal studies suggest that …